Recombinant Rat Sec1 family domain-containing protein 1 (Scfd1)
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中文名稱：大鼠Scfd1重組蛋白
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貨號：CSB-EP726823RA-B
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說明書：
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規格：
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來源：E.coli
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共軛：Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他：
產品詳情
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純度：>85% (SDS-PAGE)
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基因名：Scfd1
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Uniprot No.：
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別名：Scfd1; Ra410; Sly1; Stxbp1l2; Sec1 family domain-containing protein 1; SLY1 homolog; Sly1p; Syntaxin-binding protein 1-like 2; Vesicle transport-related protein Ra410
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種屬：Rattus norvegicus (Rat)
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蛋白長度：full length protein
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表達區域：1-637
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氨基酸序列MVGSKMAASI RERQTVALKR MLNFNVPHVK NSPGEPVWKV LIYDRFGQDI ISPLLSVKEL RDMGITLHLL LHSDRDPIRD VPAVYFVMPT EENIDRLCQD LRNQLYESYY LNFISAISRS KLEDIANAAL AANAVTQVAK VFDQYLNFIT LEEDMFVLCN QNKELVSYRA INRPDITDTE METVMDTIVD SLFCFFVTLG AVPIIRCSRG TAAEMVAVKL DKKLRENLRD ARNSLFTGDP LGTGQFSFQR PLLVLVDRNI DLATPLHHTW TYQALVHDVL DFHLNRVNLE ESTGVENSPT GARPKRKNKK SYDLTPVDKF WQKHKGSPFP EVAESVQQEL ESYRAQEDEV KRLKSIMGLE GEDEGAISML SDNTAKLTSA VSSLPELLEK KRLIDLHTNV ATAVLEHIKA RKLDVYFEYE EKIMSKTTLD KSLLDVISDP DAGTPEDKMR LFLIYYISAQ QAPSEVDLEQ YKKALTDAGC NLSPLQYIKQ WKAFAKMAST PASYGNTTTK PMGLLSRVMN TGSQFVMEGV KNLVLKQQNL PVTRILDNLM EMKSNPETDD YRYFDPKMLR SNDSSVPRNK SPFQEAIVFV VGGGNYIEYQ NLVDYIKGKQ GKHILYGCSE IFNATQFIKQ LSQLGQK
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蛋白標簽：Tag?type?will?be?determined?during?the?manufacturing?process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
產品提供形式：Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
復溶：We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事項：Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet ：Please contact us to get it.
產品評價
靶點詳情
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功能：Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi.
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基因功能參考文獻：
- results argue that although rsly1 does not seem to regulate the availability of syntaxin 5, its function is intimately associated with syntaxin binding, perhaps promoting a later step in SNARE complex formation or function PMID: 14565970
- These results suggest that RA410/Sly1 plays an important cytoprotective role in MPP+ and 6-OHDA-induced cellular perturbation. PMID: 15649705
- elucidated the structure in solution of the isolated N-terminal domain of rat Sly1 and analyzed its complex with an N-terminal peptide of rat syntaxin 5 by NMR spectroscopy PMID: 15670607
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亞細胞定位：Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
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蛋白家族：STXBP/unc-18/SEC1 family
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組織特異性：Highly expressed in testis. Detected at lower levels in brain, astrocytes, heart and small intestine.
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