Recombinant Rat Protein phosphatase 1 regulatory subunit 14D (Ppp1r14d)

中文名稱：

大鼠Ppp1r14d重組蛋白
貨號：

CSB-YP816996RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Ppp1r14d重組蛋白
貨號：

CSB-EP816996RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Ppp1r14d重組蛋白
貨號：

CSB-EP816996RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Ppp1r14d重組蛋白
貨號：

CSB-BP816996RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Ppp1r14d重組蛋白
貨號：

CSB-MP816996RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ppp1r14d
Uniprot No.：

Q8K3F4
別名：

Ppp1r14d; Gbpi; Protein phosphatase 1 regulatory subunit 14D; Gastrointestinal and brain-specific PP1-inhibitory protein 1; GBPI-1
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-146
氨基酸序列

MLSSSAASCT SPNPDTDNPD KKVRWSSEKR RRASSTDSES KTHLDISKLP RSRRPSRLTV KYDRGHLQRW LEMEQWVDAQ VQELFQGQAD TSEPEIDLEA LMELSTDEQR TQLEAILQDC PGNREPFISE LLSQLKRLRR LSRPSK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
基因功能參考文獻：
1. Brain PPP1R14D is upregulated in alloxan diabetes. It inhibits the function of PP1, switches-on glycogen breakdown and switches-off glycogen synthesis due to lack of insulin. PMID: 21112318
2. PP-1 activity due to a decrease in cyclic GMP-PKG modulation plays a role for the age-related reduction of alpha(2/3)-Na,K-ATPase activity in rat cerebellum. PMID: 17537548
3. A gastrointestinal- and brain-specific PP1 inhibitory protein (GBPI-1)is activated by PKC phosphorylation. A longer GBPI-2 splice variant mRNA is found in testis. PMID: 12974676
亞細胞定位：

Cytoplasm.
蛋白家族：

PP1 inhibitor family
數據庫鏈接：

KEGG: rno:259226

UniGene: Rn.162687