Recombinant Rat Protein VAC14 homolog (Vac14)

中文名稱：

大鼠Vac14重組蛋白
貨號：

CSB-YP773919RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Vac14重組蛋白
貨號：

CSB-EP773919RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Vac14重組蛋白
貨號：

CSB-EP773919RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Vac14重組蛋白
貨號：

CSB-BP773919RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Vac14重組蛋白
貨號：

CSB-MP773919RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Vac14
Uniprot No.：

Q80W92
別名：

Vac14; Protein VAC14 homolog
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-783
氨基酸序列

MNPEKDFAPL TPNIVRALND KLYEKRKVAA LEIEKLVRDF VAQNNTVQIK HVIQTLSQEF ALSQHPHSRK GGLIGLAACS IALGKDSGLY LKELIEPVLT CFNDADSRLR YYACEALYNI VKVARGAVLP HFNVLFDGLS KLAADPDPNV KSGSELLDRL LKDIVTESSK FDLVGFIPLL RERIYSNNQY ARQFIISWIL VLVSVPDINL LDYLPEILDG LFQILGDNGK EIRKMCEVVL GEFLKEIKKN PSSVKFAEMA NILVIHCQTT DDLIQLTAMC WMREFIQLAG RVMLPYSSGI LTAVLPCLAY DDRKKSIKEV ANVCNQSLMK LVTPEDDEPD EPKSVAQKQT EPNPEDSLPK QEGTASGGAS GPCDSSFGSG ISVFTSASTD RAPVTLHLDG IVQVLNCHLS DTTIGMMTRI AVLKWLYHLY IKTPRKMFRH TDSLFPILLQ TLSDESDEVV LKDLEVLAEI ASSPAGQTDD PGAPDGPDLQ VNHSELQVPT SGRANLLNPP NTKGLECSPS TPTMNSYFYK FMINLLQTFS SERKLLEARG PFIIRQLCLL LNAENIFHSM ADILLREEDL KFASTMVHTL NTILLTSTEL FQLRNQLKDL KTLESQNLFC CLYRSWCHNP VTTVSLCFLT QNYRHAYDLI QKFGDLEVTV DFLTEVDKLV QLIECPIFTY LRLQLLDVKN NPYLMKALYG LLMLLPQSSA FQLLSHRLQC VPNPELLQTE DCLKAAPKSQ KGDSPSIDYT ELLQHFEKVQ KQHLEVRHQR SGRGDHLDRR VVL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Scaffold protein component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Pentamerizes into a star-shaped structure and nucleates the assembly of the complex. The pentamer binds a single copy each of PIKFYVE and FIG4 and coordinates both PIKfyve kinase activity and FIG4 phosphatase activity, being required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
基因功能參考文獻：
1. This paper describes a related gene in mouse. PMID: 12719380
亞細胞定位：

Endosome membrane. Microsome membrane.
蛋白家族：

VAC14 family
組織特異性：

Expressed in brain, lung, kidney and testis with highest levels in brain and testis.
數據庫鏈接：

KEGG: rno:307842

STRING: 10116.ENSRNOP00000023383

UniGene: Rn.46366