Recombinant Rat PEX5-related protein (Pex5l)

中文名稱：

大鼠Pex5l重組蛋白
貨號：

CSB-YP838789RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Pex5l重組蛋白
貨號：

CSB-EP838789RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Pex5l重組蛋白
貨號：

CSB-EP838789RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Pex5l重組蛋白
貨號：

CSB-BP838789RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Pex5l重組蛋白
貨號：

CSB-MP838789RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Pex5l
Uniprot No.：

Q925N3
別名：

Pex5l; Pex2; Pex5r; Trip8b; PEX5-related protein; PEX5-like protein; Peroxin-5-related protein; TPR-containing Rab8b-interacting protein; Tetratricopeptide repeat-containing Rab8b-interacting protein; Pex5Rp; TRIP8b
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-602
氨基酸序列

MYQGHMQGKG SRAADKAVAM VMKEIPREES AEEKPLLTMT SQLVNEQQES RPLLSPSIDD FLCETKSEAI AKPVTSNTAV LTTGLDLLDL SEPVSQTQTK AKKSESSSKS SSLKKKADGS DLISADAEQR AQALRGPETS SLDLDIQTQL EKWDDVKFHG DRTSKGHLMA ERKSCSSRAG SKELLWSSEH RSQPELSTGK SALNSESASE LELVAPAQAR LTKEHRWGSA LLSRNHSLEE EFERAKAAVE SDTEFWDKMQ AEWEEMARRN WISENQEAQN QVTVSASEKG YYFHTENPFK DWPGAFEEGL KRLKEGDLPV TILFMEAAIL QDPGNAEAWQ FLGITQAENE NEQAAIVALQ RCLELQPNNL KALMALAVSY TNTSHQQDAC EALKNWIKQN PKYKYLVKNK KGSPGLTRRM SKSPVDSSVL EGVKDLYLEA AHQNGDMIDP DLQTGLGVLF HLSGEFNRAI DAFNAALTVR PEDYSLWNRL GATLANGDRS EEAVEAYTRA LEIQPGFIRS RYNLGISCIN LGAYREAVSN FLTALSLQRK SRNQQQVPHP AISGNIWAAL RIALSLMDQP ELFQAANLGD LDVLLRAFNL DP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence.
基因功能參考文獻：
1. Nedd4-2 plays an important role in the regulation of HCN1 trafficking and may compete with TRIP8b(1a-4) in this process PMID: 24451387
2. Our data suggest complex regulatory functions of TRIP8b in neuronal endocytosis through independent interaction with membrane proteins and components of the clathrin coat PMID: 21749376
3. A role of TRIP8b in receptor-mediated endocytosis. PMID: 18620529
4. although TRIP8b exists in multiple splice isoforms, our data suggest that the predominant role of this protein in brain is to promote h channel surface expression and enhance its current PMID: 19439603
亞細胞定位：

Cytoplasm. Membrane; Peripheral membrane protein. Note=Some fraction is membrane associated via its interaction with RAB8B.
蛋白家族：

Peroxisomal targeting signal receptor family
組織特異性：

Brain specific.
數據庫鏈接：

KEGG: rno:286937

STRING: 10116.ENSRNOP00000015200

UniGene: Rn.207886