Recombinant Rat Nuclear receptor subfamily 2 group C member 1 (Nr2c1)

中文名稱：

大鼠Nr2c1重組蛋白
貨號：

CSB-YP819785RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Nr2c1重組蛋白
貨號：

CSB-EP819785RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Nr2c1重組蛋白
貨號：

CSB-EP819785RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Nr2c1重組蛋白
貨號：

CSB-BP819785RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Nr2c1重組蛋白
貨號：

CSB-MP819785RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nr2c1
Uniprot No.：

Q8VIJ4
別名：

Nr2c1; Tr2; Nuclear receptor subfamily 2 group C member 1; Orphan nuclear receptor TR2; Testicular receptor 2
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-590
氨基酸序列

MATIEEIAHQ IIDQQMGEIV TEQQTGQKIQ IVTALDHSTQ GKQFILANHE GSTPGKVFLT TPDAAGVNQL FFASPDLSTP HLQLLTENSP DQGPNKVFDL CVVCGDKASG RHYGAITCEG CKGFFKRSIR KNLVYSCRGS KDCIINKHHR NRCQYCRLQR CIAFGMKQDS VQCERKPIEV SREKSSNCAA STEKIYIRKD LRSPLAATPT FVTDSETARS TGLLDSGMFV NIHPSGIKTE PALLMTPDKA ESCQGDLGTL ASVVTSLANL GKAKDLSHCG GDLPVVQSLR NGDTSFGAFH QDIQTNGDVS RAFDNLAKAL TPGENPACQS PGESMEGSTH LIAGEPSCME REGPLLSDSH VVFRLTMPSP MPEYLNVHYI GESASRLLFL SMHWALSIPS FQALGQENSI SLVKAYWNEL FTLGLAQCWQ VMNVATILAT FVNCLHNSLQ QDKMSPERRK LLMEHIFKLQ EFCNSMVKLC IDGHEYAYLK AIVLFSPDHP GLENMELIEK FQEKAYVEFQ DYITRTYPDD TYRLSRLLLR LPALRLMNAT ITEELFFKGL IGNVRIDSVI PHILKMEPAD YNSQIIGHSL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes including ESR1 and RARB. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Also activator of OCT4 gene expression. Plays a fundamental role in early embryogenesis and regulates embryonic stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
亞細胞定位：

Nucleus. Nucleus, PML body.
蛋白家族：

Nuclear hormone receptor family, NR2 subfamily
數據庫鏈接：

KEGG: rno:252924

STRING: 10116.ENSRNOP00000009578

UniGene: Rn.79894