Recombinant Rat NUAK family SNF1-like kinase 2 (Nuak2)

中文名稱：

大鼠Nuak2重組蛋白
貨號：

CSB-YP731434RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Nuak2重組蛋白
貨號：

CSB-EP731434RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Nuak2重組蛋白
貨號：

CSB-EP731434RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Nuak2重組蛋白
貨號：

CSB-BP731434RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Nuak2重組蛋白
貨號：

CSB-MP731434RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nuak2
Uniprot No.：

Q66HE5
別名：

Nuak2; NUAK family SNF1-like kinase 2; EC 2.7.11.1; SNF1/AMP kinase-related kinase; SNARK
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-630
氨基酸序列

MESVALHRRG NLAPSASALA TESARPLADR LIKSPKPLMK KQAVKRHHHK HNLRHRYEFL ETLGKGTYGK VKKARESSGR LVAIKSIRKD KIKDEQDLLH IRREIEIMSS LNHPHIIAIH EVFENSSKIV IVMEYASRGD LYDYISERPR LNERDARHFF RQIVSALHYC HQNGIVHRDL KLENILLDAS GNIKIADFGL SNLYHKGKFL QTFCGSPLYA SPEIVNGKPY VGPEVDSWSL GVLLYILVHG TMPFDGQDHK TLVKQISSGA YREPCKPSDA CGLIRWLLMV NPIRRATLED VASHWWVNWG YSTRIGEQEA LREGGHPSGD SGRASMADWL RRSSRPLLEN GAKVCSFFKQ HVPGGGSTGP GLERQHSLKK SRKENDMAQT LQNDPAEDTS SRPGKNSLKL PKGILKKKAS PSSGEVQEGP QELRPVSNTP GQPVPAIPLL PRKGILKKSR QRESGYYSSP EPSESGELLD AGDVFVSGDP MEQKSPQASG RLHRKGILKL NGKFSRTALE GTAPSTFGSL DQLASPHPTA RASRPSGAVS EDSILSSESF DQLDLPERLP ETPLRGCVSV DNLRRLEQPP SEGLKRWWQE SLGDSCFSLT DCQEVTAAYR QALGICSKLS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
基因功能參考文獻：
1. SNARK (SNF1/AMP-activated protein kinase) activity is regulated by a broad range of cellular stresses in a cell-type-specific manner. PMID: 15893879
蛋白家族：

Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily
組織特異性：

Expressed in liver, skin, testis, uterus, ovary, adrenal gland and brain (at protein level). Expressed in kidney, heart, skin, spleen, lung, uterus, liver and the exocrine and endocrine compartments of the human pancreas. A kinase-inactive isoform also ap
數據庫鏈接：

KEGG: rno:289419

STRING: 10116.ENSRNOP00000000039

UniGene: Rn.16922