Recombinant Rat Methylosome protein 50 (Wdr77)
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中文名稱：大鼠Wdr77重組蛋白
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貨號：CSB-EP703075RA-B
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說明書：
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規格：
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來源：E.coli
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共軛：Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他：
產品詳情
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純度：>85% (SDS-PAGE)
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基因名：Wdr77
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Uniprot No.：
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別名：Wdr77; Mep50; Methylosome protein 50; MEP-50; WD repeat-containing protein 77
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種屬：Rattus norvegicus (Rat)
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蛋白長度：full length protein
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表達區域：1-342
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氨基酸序列MRKESPPPLV PPAAREWNLP PNAPACMERQ LEAARYRSDG SLLLGASSLS GRCWAGSLWF FKDPSAAPNE GFCSAGVQTE AGVADLTWVG DKGILVASDS GAVELWELDE NETLIVSKFC KYEHDDIVST VTVLSSGTQA VSGSKDFCIK IWDLAQQMSL NSYRAHAGQV TCVAASPHRE TVFLSCSEDS RILLWDTRCP KPASQMGCNA SGYLPTSLAW HPQQSEIFVF GDENGSVSLV DTKNASCTLS SAVHSQCVTR LVFSPHSVPF LASLSEDCSL AVLDSSFSEV FRSRAHRDFV RDATWSPLNH SLLTTVGWDH QVIHHVVPLE PLPAPGPDSV VE
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蛋白標簽：Tag?type?will?be?determined?during?the?manufacturing?process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
產品提供形式：Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
復溶：We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事項：Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet ：Please contact us to get it.
產品評價
靶點詳情
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功能：Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
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亞細胞定位：Nucleus. Cytoplasm.
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數據庫鏈接：
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