Recombinant Rat Ermin (Ermn)

中文名稱：

大鼠Ermn重組蛋白
貨號：

CSB-YP713047RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Ermn重組蛋白
貨號：

CSB-EP713047RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Ermn重組蛋白
貨號：

CSB-EP713047RA-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Ermn重組蛋白
貨號：

CSB-BP713047RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Ermn重組蛋白
貨號：

CSB-MP713047RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ermn
Uniprot No.：

Q5RJL0
別名：

ErmnErmin; Juxtanodin; JN
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區(qū)域：

1-282
氨基酸序列

MTDTPVTLSG SECNGDRPPE NGQQPSSQTR KTTDADETQT YYGVEPSLQH LPAKENQEES GNSKGNVLPR GSEDEKILNE NTEENLFVVH QAIQDLSLQE TSAEDTVFQE GHPWKKIPLN SHNLDMSRQK ERIVHQHLEQ REDESAAHQA TEIEWLGFQK SSQVDILHSK CDEEEEVWNE EINEEDVDEC AEDEGEDEVR VIEFKRKYRE GSPLKEESLA REDSPLSSPS SQPGTPDEQL VLGKKGDIAR NSYSRYNTIS YRKIRKGNTK QRIDEFESMM HL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.
基因功能參考文獻：
1. Data indicate that juxtanodin is non-globular and monomeric in solution. PMID: 23198089
2. Nkx2.2 is one of the essential transcription factors delivering the specificity of JN promoter in oligodendrocytes. PMID: 21221725
3. Specific phosphorylation of JN might serve as an important mechanism regulating JN functions. PMID: 20610382
4. Juxtanodin is an oligodendroglial protein that promotes cellular arborization and 2',3'-cyclic nucleotide-3'-phosphodiesterase trafficking. PMID: 16051705
5. These results identify JN as a marker protein for OE sustentacular cells, and support the glia-like nature of OE sustentacular cells. PMID: 19332107
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亞細胞定位：

Cytoplasm, cytoskeleton.
組織特異性：

Expressed specifically by the oligodendrocytes. Highest expression seen in the spinal cord followed by brainstem, cerebellum, thalamus, and hypothalamus. In the myelin sheath, found mainly in the abaxon and the lateral few terminal loops. Its apposition t
數(shù)據(jù)庫鏈接：

KEGG: rno:295619

STRING: 10116.ENSRNOP00000029247

UniGene: Rn.20243