Recombinant Rat Electroneutral sodium bicarbonate exchanger 1 (Slc4a8), partial

中文名稱：

大鼠Slc4a8重組蛋白
貨號：

CSB-YP754339RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Slc4a8重組蛋白
貨號：

CSB-EP754339RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Slc4a8重組蛋白
貨號：

CSB-EP754339RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Slc4a8重組蛋白
貨號：

CSB-BP754339RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Slc4a8重組蛋白
貨號：

CSB-MP754339RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Slc4a8
Uniprot No.：

Q6RVG2
別名：

Slc4a8; Ndcbe1Electroneutral sodium bicarbonate exchanger 1; Electroneutral Na+-driven Cl-HCO3 exchanger; Solute carrier family 4 member 8; k-NBC3
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
基因功能參考文獻：
1. These findings suggest that NDCBE can regulate glutamatergic transmission throughout the brain PMID: 22102085
2. The sodium-driven chloride/bicarbonate exchanger NDCBE is upregulated in multiple neurons in a cell type-specific manner. PMID: 21195699
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Anion exchanger (TC 2.A.31) family
組織特異性：

Expressed in the Purkinje cells and dendrites in the molecular layer of the cerebellum (at protein level). Strong expression observed in testis and moderate expression in kidney inner medulla, the submandibular gland, eye, cerebrum and cerebellum.
數據庫鏈接：

KEGG: rno:315311

STRING: 10116.ENSRNOP00000043825

UniGene: Rn.210164