Recombinant Rat Dysbindin (Dtnbp1)

中文名稱：

大鼠Dtnbp1重組蛋白
貨號：

CSB-YP686671RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Dtnbp1重組蛋白
貨號：

CSB-EP686671RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Dtnbp1重組蛋白
貨號：

CSB-EP686671RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Dtnbp1重組蛋白
貨號：

CSB-BP686671RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Dtnbp1重組蛋白
貨號：

CSB-MP686671RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Dtnbp1
Uniprot No.：

Q5M834
別名：

Dtnbp1; Bloc1s8Dysbindin; Biogenesis of lysosome-related organelles complex 1 subunit 8; BLOC-1 subunit 8; Dysbindin-1; Dystrobrevin-binding protein 1
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-352
氨基酸序列

MLETLRERLL SVQQDFTSGL KTLSDKSKEA KVKSRPRTAP YLPKYSAGLD LLSRYEDTWA ALHRRAKECA DAGELVDSEV VMLSAHWEKK RTSLAELQEQ LQQLPALLQD VESLMASLAH LETSFEEVEN HLLHLEDLCG QCELERHKQA HARHLEDYKK SKRKELEAFK AELDTEHAQK ILEMEHTQQL KLKERQKFFE EAFQQDMEQY LSTGHLQIAE RREPMGSMSS MEVNVDVLEQ MDLMDLSDQE ALDVFLNSGG EDNTVISPGL EMESNPSQNE MNLQIPNPSE SASQPPASPS ACTDLDTADA PLIQADEEEV QVDTALVTLN TDRKSTPGVS DDSDQCDSTQ DI
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.
亞細胞定位：

Cytoplasm. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Melanosome membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Cell junction, synapse, postsynaptic density. Cell junction, synapse, presynaptic cell membrane. Endoplasmic reticulum.
蛋白家族：

Dysbindin family
組織特異性：

Detected in hippocampus neurons (at protein level). Ubiquitously expressed. The highest expression is observed in testis, liver, kidney, brain, heart and lung. In the brain, found primarily in axon bundles and axon terminals, notably in the cerebellum and
數據庫鏈接：

KEGG: rno:641528

STRING: 10116.ENSRNOP00000067149

UniGene: Rn.187290