Recombinant Rat DnaJ homolog subfamily B member 6 (Dnajb6)

中文名稱：

大鼠Dnajb6重組蛋白
貨號：

CSB-YP734912RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Dnajb6重組蛋白
貨號：

CSB-EP734912RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Dnajb6重組蛋白
貨號：

CSB-EP734912RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Dnajb6重組蛋白
貨號：

CSB-BP734912RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Dnajb6重組蛋白
貨號：

CSB-MP734912RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Dnajb6
Uniprot No.：

Q6AYU3
別名：

Dnajb6; DnaJ homolog subfamily B member 6; Heat shock protein J2; HSJ-2; Hsp40 homolog; MRJ; MSJ-1
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-357
氨基酸序列

VDYYEVLGV QRHASPEDIK KAYRKQALKW HPDKNPENKE EAERKFKQVA EAYEVLSDAK KRDIYDKYGK EGLNGGGGGG GSHFDSPFEF GFTFRNPDDV FREFFGGRDP FSFDFFEDPF DDFFGNRRGP RGSRSRGAGS FFSAFSGFPS FGSGFPAFDT GFTPFGSLGH GGLTSFSSAS FGGSGMGNFK SISTSTKIVN GKKITTKRIV ENGQERVEVE EDGQLKSLTI NGVADENALA EECRRRGQPT PALAPGPAPA PARVPSQARP PTPAPTPAPA QTPAPSVSTR PQKPPRPAPT AKLVSKSNWE DEEQDRQRVP GNCDAPMTSA GLKEGGKRKK QKQKEDSKKK KSTKGNH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
基因功能參考文獻：
1. These results conclude that neurotoxicity resulting from elevated DNAJB6 is cell cycle dependent. PMID: 26476842
亞細胞定位：

Cytoplasm, perinuclear region. Nucleus. Cytoplasm, myofibril, sarcomere, Z line.
組織特異性：

Highest levels of expression found in brain and retina, and lower levels in heart, kidney, liver and placenta.
數據庫鏈接：

KEGG: rno:362293

STRING: 10116.ENSRNOP00000041883

UniGene: Rn.129050