Recombinant Rat Diphosphomevalonate decarboxylase (Mvd)

中文名稱：

大鼠Mvd重組蛋白
貨號：

CSB-YP726822RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Mvd重組蛋白
貨號：

CSB-EP726822RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Mvd重組蛋白
貨號：

CSB-EP726822RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Mvd重組蛋白
貨號：

CSB-BP726822RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Mvd重組蛋白
貨號：

CSB-MP726822RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mvd
Uniprot No.：

Q62967
別名：

Mvd; Mpd; Diphosphomevalonate decarboxylase; EC 4.1.1.33; Mevalonate; diphospho)decarboxylase; MDDase; Mevalonate pyrophosphate decarboxylase
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-401
氨基酸序列

ASEKPQDLM VTCTAPVNIA VIKYWGKRDE ALILPINPSL SVTLHQDQLK TTTTAAISKD FTEDRIWLNG REEDVGQPRL QACLREIRRL ARKRRSTGDG DALPLSLGYK VHVASVNNFP TAAGLASSAA GYACLAYTLA RVYGVEGDLS EVARRGSGSA CRSLYGGFVE WQMGEQADGK DSIARQIAPE WHWPQLRVLI LVVSAEKKPT GSTVGMQTSV ATSTLLKFRA ESIVPERMKE MTRCIQEQDF QAFAQLTMKD SNQFHATCLD TFPPISYLND TSRRIIQLVH RFNAHHGQTK VAYTFDAGPN AVIFTLEDTV AEFVAAVRHS FPPAANGDKF LKGLQVAPVL LSDELKTSLA TEPSPGGVQY IIATQVGPGP QVLDDPHHHL LGPDGLPQRD L
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
基因功能參考文獻：
1. These results indicate that the upregulation of miR-214 and downregulation of MPD transcription in the liver both play a role in the development of hypocholesterolemia PMID: 26158200
2. The 45-kDa isoform of mevalonate pyrophosphate decarboxylase has been detected in the matrix of the liver peroxisomes, whereas the 37-kDa form localizes primarily to the liver cytosol. PMID: 11767099
3. Distribution of mevalonate pyrophosphate decarboxylase is significantly reduced in the liver as well as brain of the stroke-prone spontaneously hypertensive rat from the age of two weeks, compared to that of the normotensive Wistar Kyoto strain. PMID: 11767113
亞細胞定位：

Cytoplasm.
蛋白家族：

Diphosphomevalonate decarboxylase family
數據庫鏈接：

KEGG: rno:81726

STRING: 10116.ENSRNOP00000018145

UniGene: Rn.10288