Recombinant Rat Cysteine and glycine-rich protein 2 (Csrp2)

中文名稱：

Recombinant Rat Cysteine and glycine-rich protein 2(Csrp2)
貨號：

CSB-YP006084RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat Cysteine and glycine-rich protein 2(Csrp2)
貨號：

CSB-EP006084RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat Cysteine and glycine-rich protein 2(Csrp2)
貨號：

CSB-EP006084RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Cysteine and glycine-rich protein 2(Csrp2)
貨號：

CSB-BP006084RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Cysteine and glycine-rich protein 2(Csrp2)
貨號：

CSB-MP006084RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Csrp2
Uniprot No.：

Q62908
別名：

Csrp2; Smlim; Cysteine and glycine-rich protein 2; Cysteine-rich protein 2; CRP2; Smooth muscle cell LIM protein; SmLIM
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-193
氨基酸序列

MPVWGGGNKC GACGRTVYHA EEVQCDGRTF HRCCFLCMVC RKNLDSTTVA IHDEEIYCKS CYGKKYGPKG YGYGQGAGTL NMDRGERLGI KPESAQPHRP TTNPNTSKFA QKYGGAEKCS RCGDSVYAAE KIIGAGKPWH KNCFRCAKCG KSLESTTLTE KEGEIYCKGC YAKNFGPKGF GYGQGAGALV HAQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.
基因功能參考文獻：
1. In rats, estrogen was found to up-regulate SmLIM genes in smooth muscle vascular cells. PMID: 15219810
2. CRP2 acted as a potent transcription coadaptor that remodeled silent cardiac myocyte chromatin and directed serum response factor-dependent smooth muscle gene activity. PMID: 17185421
3. TGFbeta activates ATF2 phosphorylation and Csrp2 gene expression via a CRE promoter element. PMID: 18387947
4. Results demonstrated that in undifferentiated olfactory precursor cells Csrp2 was distributed both in the nucleus and the cytoplasm, whereas CRIP2 was predominantly localized in the cytoplasm. PMID: 19364329
亞細胞定位：

Nucleus.
組織特異性：

Highly expressed in the aorta; weakly found in the kidney, thymus, and intestine. Barely detectable in brain, testis, esophagus, lung, liver, aortic adventitia, vena cava, or uterus; not present in heart and skeletal muscle.
數據庫鏈接：

KEGG: rno:29317

STRING: 10116.ENSRNOP00000061356

UniGene: Rn.94754