Recombinant Rat Aryl hydrocarbon receptor repressor (Ahrr)
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中文名稱：Recombinant Rat Aryl hydrocarbon receptor repressor(Ahrr)
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貨號：CSB-YP762298RA
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說明書：
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規(guī)格：
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來源：Yeast
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其他：
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中文名稱：Recombinant Rat Aryl hydrocarbon receptor repressor(Ahrr)
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貨號：CSB-EP762298RA
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說明書：
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規(guī)格：
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來源：E.coli
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其他：
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中文名稱：Recombinant Rat Aryl hydrocarbon receptor repressor(Ahrr)
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貨號：CSB-EP762298RA-B
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說明書：
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規(guī)格：
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來源：E.coli
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共軛：Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他：
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中文名稱：Recombinant Rat Aryl hydrocarbon receptor repressor(Ahrr)
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貨號：CSB-BP762298RA
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說明書：
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規(guī)格：
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來源：Baculovirus
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其他：
產(chǎn)品詳情
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純度：>85% (SDS-PAGE)
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基因名：Ahrr
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Uniprot No.：
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別名：Ahrr; Aryl hydrocarbon receptor repressor; AhR repressor; AhRR
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種屬：Rattus norvegicus (Rat)
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蛋白長度：full length protein
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表達區(qū)域：1-701
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氨基酸序列MMIPSGECTY AGRKRRKPIQ KRRLTMGTEK SNPSKRHRDR LNTELDHLAS LLPFSPDIIS KLDKLSVLRL SVSYLRVKSF FQALQETCVW SAPALSPEDH SSRGFPVQEG RLLLESLNGF ALVVSAEGMI FYASATIVDY LGFHQTDVMH QNIYDYIHVD DRQDFCRQLH WAMDPPQVVF GQSPHADTDN TVLGKLLRAQ EGGKGLPSEY SAFLTRCFIC RVRCLLDSTS GFLTMQFQGK LKFLFGQKKK TPSGTALPPR LSLFCIVAPV LPSVTEMKMK SAFLKAKHRA DIVVTMDSRA KAVTSLCESE LHPKLNYLAG RSNGENVISL FRGQTDRSHW TRALARSSCL CLRGGPDLLD PKGTSGDREE DDQKHILRRS PGARGQREMH KYSYGLETPV HLRHLDWSTE QRSQEGTTKL TRQPSKSEPS TCLVPHGSCV PYPGSQGMFS ASNMASFRES LDHPTGTYCS QMNRPLPDIH QGQVDPSTCH IPQGSLGSRI PLSGMQCFTA RGFSTEDAKL PSLPVNIGTP CNPVLSLEVP IKMENESGSQ DIVEASTTSC VWLGTGDMTR RHLVGFPARM HLKTEPDYRQ QVCTPHRGHG ILGTNPHSRD TVGSCREHAP LYSAHCTCLS PEPPHHLFMC SHSESQHPSL DQDCRAPIVK REPLDSPSWA APGHVTVPRM FPKNASITVI PSKGSDGIFL P
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蛋白標簽：Tag?type?will?be?determined?during?the?manufacturing?process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
產(chǎn)品提供形式：Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
復溶：We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質(zhì)期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事項：Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet ：Please contact us to get it.
產(chǎn)品評價
靶點詳情
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功能：Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
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基因功能參考文獻：
- The expression of AHRR was upregulated in the kidneys of rats with chronic kidney disease. PMID: 28485216
- the constitutive expression of AhRR mRNA was prominent in males when compared with females in parallel with the sexual difference in AhR PMID: 16595894
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亞細胞定位：Cytoplasm. Nucleus.
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組織特異性：Highly expressed in testis and weakly expressed in heart and liver. Highly expressed in small intestine and cecum in a male-dominant sexual dimorphic fashion.
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數(shù)據(jù)庫鏈接：
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