Recombinant Rat Ankyrin repeat and SOCS box protein 2 (Asb2)

中文名稱：

Recombinant Rat Ankyrin repeat and SOCS box protein 2(Asb2)
貨號：

CSB-YP716389RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat Ankyrin repeat and SOCS box protein 2(Asb2)
貨號：

CSB-EP716389RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat Ankyrin repeat and SOCS box protein 2(Asb2)
貨號：

CSB-EP716389RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Ankyrin repeat and SOCS box protein 2(Asb2)
貨號：

CSB-BP716389RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Ankyrin repeat and SOCS box protein 2(Asb2)
貨號：

CSB-MP716389RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Asb2
Uniprot No.：

Q5U2S6
別名：

Asb2; Ankyrin repeat and SOCS box protein 2; ASB-2
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-634
氨基酸序列

MSTEISTRGR QRAIGHEEYS LYSSLSEEEL VQMAIEQSLA DKTRGPTPAE TSVSSQTNHQ PGHIHPWTRS SSPPESPPAR APLGLFQGVM QKYSSNLFKT SQMAAMDPVL KAIKEGDEEA LKAMIQDGKN LAEPNKEGWL PLHEAAYYGK LGCLKVLQRA YPGTIDQRTL QEETALYLAT CREHLDCLLS LLQAGAEPDI SNKSRETPLY KACERKNAEA VRILVQYNAD ANHRCNRGWT ALHESVSRND LEVMEILVSG GAKVEAKNVY SITPLFVAAQ SGQLEALRFL AKHGADINTQ ASDSASALYE ACKNEHEDVV EFLLSQGADA NKANKDGLLP LHVASKKGNY RIVQMLLPVT SRTRVRRSGI SPLHLAAERN HDAVLEALLA ARFDVNTPLA PERARLYEDR RTSALYFAVV NNNVYATELL LLAGADPNRD VISPLLVAIR HGCLRTMQLL LDHGANIDAY IATHPTAFPA TIMFAMKCLS LLKFLMDLGC DGEPCFSCLY GNGPHPPAPR SGRFNDAPVD DKAPSVVQFC EFLSAPEVSR WAGPIIDVLL DYVGNVQLCS RLKEHIDSFE DWAVIKEKAE PPRPLAHLCR LRVRKAIGKY RIKLLDTLPL PGRLIRYLKY ENTQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Mediates Notch-induced ubiquitination and degradation of substrates including E2A and JAK2. Required during embryonic heart development for complete heart looping. Required for cardiomyocyte differentiation. Involved in myogenic differentiation and targets filamin FLNB for proteasomal degradation but not filamin FLNA. Also targets DES for proteasomal degradation. Acts as a negative regulator of skeletal muscle mass.
亞細胞定位：

Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, myofibril, sarcomere, Z line.
蛋白家族：

Ankyrin SOCS box (ASB) family
數據庫鏈接：

KEGG: rno:299266

STRING: 10116.ENSRNOP00000012045

UniGene: Rn.98677