Recombinant Rat Actin-binding Rho-activating protein (Abra)

中文名稱：

Recombinant Rat Actin-binding Rho-activating protein(Abra)
貨號：

CSB-YP809116RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat Actin-binding Rho-activating protein(Abra)
貨號：

CSB-EP809116RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat Actin-binding Rho-activating protein(Abra)
貨號：

CSB-EP809116RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Actin-binding Rho-activating protein(Abra)
貨號：

CSB-BP809116RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Actin-binding Rho-activating protein(Abra)
貨號：

CSB-MP809116RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Abra
Uniprot No.：

Q8K4K7
別名：

Abra; Ms1Actin-binding Rho-activating protein; MS1; Striated muscle activator of Rho-dependent signaling; STARS
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-375
氨基酸序列

MAPGETEREA GPAKSALQKV RRATLVINLA RGWQQWANEN STRQAQEPAG WLPGATQDLP HTPKEPGPRQ HAPKPPSPKP DGDREGRGSE EATEVSHIKR KEVTRTVVSK AYERGGDVNY LSHRYEHDGG VSEAVQPDND IDRILLSHDS PTRRRKCTNL VSELTKGWKV MEQEEPKWKS DSIDTEDSGY GGDMEERPEQ DVAQVAAARI KRPLHSQANR YSETLNCKAH RKYSQVDNLK GRWQQWADEH IQSQKLNPFS DEFDYDLAMS TRLHKGDEGY GRPKEGSKTA ERAKRAEEHI YREIMELCFV IRTMARHRRD GKIQVTFGEL FDRYVRISDK VVGILMRARK HGLVHFEGEM LWQGKDDHVV ITLLE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.
基因功能參考文獻：
1. In rat cardiomyocytes Ms1 is exclusively found in sarcomere. A nuclear localisation site in the N-terminus is required for nuclear localisation. Ms1 has the potential to act directly in the nucleus through specific interaction with DNA in development PMID: 26656831
2. The C-terminal half of the MS1 protein contains two independent F-actin binding domains. PMID: 22081479
3. Results suggest the involvement of MS1 in cellular hypertrophy and protection against apoptosis. PMID: 19686740
亞細胞定位：

Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton. Note=Localized to the I-band of the sarcomere and to a lesser extent to the sarcomeric structure between Z-lines.
組織特異性：

Predominantly expressed in heart and skeletal muscle, and expressed at lower levels in adrenal gland, brain, kidney, liver, and testis.
數據庫鏈接：

KEGG: rno:286965

STRING: 10116.ENSRNOP00000010539

UniGene: Rn.21198