Recombinant Rat Acetoacetyl-CoA synthetase (Aacs)

中文名稱：

Recombinant Rat Acetoacetyl-CoA synthetase(Aacs)
貨號：

CSB-YP001012RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat Acetoacetyl-CoA synthetase(Aacs)
貨號：

CSB-EP001012RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat Acetoacetyl-CoA synthetase(Aacs)
貨號：

CSB-EP001012RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Acetoacetyl-CoA synthetase(Aacs)
貨號：

CSB-BP001012RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Acetoacetyl-CoA synthetase(Aacs)
貨號：

CSB-MP001012RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Aacs
Uniprot No.：

Q9JMI1
別名：

AacsAcetoacetyl-CoA synthetase; EC 6.2.1.16
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-672
氨基酸序列

MSKLARLERE EIMECQVMWE PDSKKDTQMD RFRAAVGTAC GLALGNYDDL YHWSVRSYSD FWAEFWKFSG IVCSRMYDEV VDTSKGIADV PEWFRGSRLN YAENLLRHKE NDRVALYVAR EGREEIAKVT FEELRQQVAL FAAAMRKMGV KKGDRVVGYL PNSAHAVEAM LAAASIGAIW SSTSPDFGVN GVLDRFSQIQ PKLIFSVEAV VYNGKEHGHL EKLQRVVKGL PDLQRVVLIP YVLPREKIDI SKIPNSMFLD DFLASGTGAQ APQLEFEQLP FSHPLFIMFS SGTTGAPKCM VHSAGGTLIQ HLKEHVLHGN MTSSDILLYY TTVGWMMWNW MVSALATGAS LVLYDGSPLV PTPNVLWDLV DRIGITILGT GAKWLSVLEE KDMKPMETHN LHTLHTILST GSPLKAQSYE YVYRCIKSTV LLGSISGGTD IISCFMGQNS SIPVYKGEIQ ARNLGMAVEA WDEEGKTVWG ASGELVCTKP IPCQPTHFWN DENGSKYRKA YFSKYPGVWA HGDYCRINPK TGGIVMLGRS DGTLNPNGVR FGSSEIYNIV EAFDEVEDSL CVPQYNRDGE ERVVLFLKMA SGHTFQPDLV KHIRDAIRLG LSARHVPSLI LETQGIPYTI NGKKVEVAVK QVIAGKTVEH RGAFSNPESL DLYRDIPELQ DF
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development.
基因功能參考文獻：
1. Prenatal nicotine exposure can cause DNA hypermethylation of the AACS promoter in the rat fetal adrenal. PMID: 26776438
2. AACS in adipose tissue plays an important role in utilizing ketone body for the fatty acid-synthesis during adipose tissue development PMID: 16055091
3. As acetoacetyl-CoA synthetase was expressed in neural-like cells, ketone bodies are assumed to be utilized for the synthesis of lipidic substances and to cause metabolic disorders in the nervous system of genetically obese rats. PMID: 19219059
亞細胞定位：

Cytoplasm, cytosol.
蛋白家族：

ATP-dependent AMP-binding enzyme family
組織特異性：

Abundant in male subcutaneous white adipose tissue after weaning. In white adipose tissue, it is preferentially detected in mature adipocytes but not in preadipocytes. The expression in primary preadipocytes increases during the adipocyte differentiation.
數據庫鏈接：

KEGG: rno:65984

STRING: 10116.ENSRNOP00000001292

UniGene: Rn.9215