Recombinant Rat A/G-specific adenine DNA glycosylase (Mutyh)

中文名稱：

大鼠Mutyh重組蛋白
貨號：

CSB-YP840303RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Mutyh重組蛋白
貨號：

CSB-EP840303RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Mutyh重組蛋白
貨號：

CSB-EP840303RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Mutyh重組蛋白
貨號：

CSB-BP840303RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Mutyh重組蛋白
貨號：

CSB-MP840303RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mutyh
Uniprot No.：

Q8R5G2
別名：

Mutyh; Myh; Adenine DNA glycosylase; EC 3.2.2.31; MutY homolog; rMYH
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-516
氨基酸序列

MKKLRASVRS HKKQPANHKR RGKCALSSSQ AKPSGLDGLA KQKREELLKT PVSPYHLFSD IADVTAFRRN LLSWYDQEKR DLPWRKRVKE ETNLDRRAYA VWVSEVMLQQ TQVATVIDYY TRWMQKWPTL QDLASASLEE VNQLWSGLGY YSRGRRLQEG ARKVVEELGG HVPRTAETLQ QLLPGVGRYT AGAIASIAFD QVTGVVDGNV IRVLCRVRAI GADPTSSFVS HHLWDLAQQL VDPARPGDFN QAAMELGATV CTPQRPLCNH CPVQSLCRAH QRVGQGRLSA LPGSPDIEEC ALNTRQCQLC LPSTNPWDPN MGVVNFPRKA SRRPPREEYS ATCVVEQPGA TGGPLILLVQ RPNSGLLAGL WEFPSVTLEP SGQHQHKALL QELQHWSAPL PTTPLQHLGE VIHVFSHIKL TYQVYSLALE GQTPASTTLP GARWLTWEEF RNAAVSTAMK KVFRVYEEHR RGTCKGSKRP QVCTPSSRKK PSRGQQVLDR FFQRHIPTHK PNSTTQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.
基因功能參考文獻：
1. respiratory hypoxia leads to increased expression of MYH in the rat brain PMID: 11948257
2. Levels of MutY DNA glycosylase are detected in rat brain at the embryonic stage, decrease during embryonic and neonatal development, while new isoforms appear and gradually increase in the neonate and adult brain. PMID: 14690527
亞細胞定位：

Nucleus. Mitochondrion.
蛋白家族：

Nth/MutY family
組織特異性：

Expressed in brain, spleen, heart, liver and kidney.
數據庫鏈接：

KEGG: rno:170841

STRING: 10116.ENSRNOP00000024375

UniGene: Rn.44045