Recombinant Ras-related protein Rab-6.1 (rab-6.1)

中文名稱：

秀麗隱桿線蟲rab-6.1重組蛋白
貨號：

CSB-YP339426CXY
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲rab-6.1重組蛋白
貨號：

CSB-EP339426CXY
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲rab-6.1重組蛋白
貨號：

CSB-EP339426CXY-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲rab-6.1重組蛋白
貨號：

CSB-BP339426CXY
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲rab-6.1重組蛋白
貨號：

CSB-MP339426CXY
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

rab-6.1
Uniprot No.：

P34213
別名：

rab-6.1; F59B2.7; Ras-related protein Rab-6.1
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區域：

1-205
氨基酸序列

MADFTNNALK KFKLVFLGEQ SVGKTSIITR FMYDSFDNTY QATIGIDFLS KTMYLEDRTI RLQLWDTAGQ ERFRSLIPSY IRDSSVAVVV YDITNANSFH QTTKWVDDVR NERGCDVIIV LVGNKTDLAD KRQVSTEDGE KKARDLNVMF IETSAKAGYN VKQLFRKIAT ALPGIVQEET PEQPNIVIMN PPKDAEESQG RQCPC
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. In its active GTP-bound form, acts redundantly with rab-6.2 (in its active GTP-bound form) to positively regulate the retrograde trafficking of cargo molecules from endosomes to Golgi structures. Required for the retrograde trafficking of glr-1, a subunit of AMPA-type glutamate receptors (AMPRs), out of early endosomes and into the Golgi compartment in neurons. Together with rab-6.2, promotes the retrograde trafficking of mig-14 from endosomes to Golgi structures in the intestine. In oocytes, in its active GTP-bound form, involved in the membrane fusion and exocytosis of secretory vesicles (cortical granules) to play a role in the remodeling of the embryo surface following fertilization. Recruits sep-1 to cortical granules (derived from the Golgi complex) for exocytosis during the oocyte-to-embryo transition. Required for seam cell division and alae formation. Promotes spontaneous reversals in locomotion.
基因功能參考文獻：
1. RAB-6.1 is an important molecule for the timely exocytosis of the cortical granules during oocyte-to-embryo transition. PMID: 22992455
亞細胞定位：

Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendrite. Perikaryon. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle.
蛋白家族：

Small GTPase superfamily, Rab family
組織特異性：

Highly expressed in body wall muscle, intestine, somatic gonad, distal tip cells, vulva, and neurons including AVB, AVD, RIG, and PVC (at protein level). Not expressed in AVA and RMDV neurons.
數據庫鏈接：

KEGG: cel:CELE_F59B2.7

STRING: 6239.F59B2.7.1

UniGene: Cel.10374