Recombinant Pseudomonas aeruginosa Porin P (oprP)

中文名稱：

銅綠假單胞菌oprP重組蛋白
貨號：

CSB-YP361596EZX
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

銅綠假單胞菌oprP重組蛋白
貨號：

CSB-EP361596EZX-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

銅綠假單胞菌oprP重組蛋白
貨號：

CSB-BP361596EZX
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

銅綠假單胞菌oprP重組蛋白
貨號：

CSB-MP361596EZX
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

oprP
Uniprot No.：

P05695
別名：

oprP; PA3279; Porin P; Outer membrane protein D1
種屬：

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
蛋白長度：

Full Length of Mature Protein
表達區域：

30-440
氨基酸序列

G TVTTDGADIV IKTKGGLEVA TTDKEFSFKL GGRLQADYGR FDGYYTNNGN TADAAYFRRA YLEFGGTAYR DWKYQINYDL SRNVGNDSAG YFDEASVTYT GFNPVNLKFG RFYTDFGLEK ATSSKWVTAL ERNLTYDIAD WVNDNVGTGI QASSVVGGMA FLSGSVFSEN NNDTDGDSVK RYNLRGVFAP LHEPGNVVHL GLQYAYRDLE DSAVDTRIRP RMGMRGVSTN GGNDAGSNGN RGLFGGSSAV EGLWKDDSVW GLEGAWALGA FSAQAEYLRR TVKAERDRED LKASGYYAQL AYTLTGEPRL YKLDGAKFDT IKPENKEIGA WELFYRYDSI KVEDDNIVVD SATREVGDAK GKTHTLGVNW YANEAVKVSA NYVKAKTDKI SNANGDDSGD GLVMRLQYVF
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate.
基因功能參考文獻：
1. Our analyzes show that OprO, and to a lesser degree OprP, have unexpected very high permeability to fosfomycin, so the antibiotic should be a potentially excellent alternative choice for the control of Pseudomonas aeruginosa infections. PMID: 29198700
2. The results suggest that trimerization is crucial for both structure and function of general porin OmpF in E. coli, whereas being trimer in substrate-specific channel OprP supports a pore function in Pseudomonas aeruginosa. PMID: 26895142
3. Study used x-ray crystallography, free-energy molecular dynamics (MD) simulations, and electrophysiology to uncover the atomic basis for the different substrate specificity of OprP and OprO PMID: 26445443
4. Data indicate the role of the R133 residue - particularly its charge and ability to change the solvation behavior of the permeating ion - in the structure-function relationship of outer membrane porin OprP. PMID: 23875754
亞細胞定位：

Cell outer membrane; Multi-pass membrane protein.
蛋白家族：

OprO/OprP family
數據庫鏈接：

KEGG: pae:PA3279

STRING: 208964.PA3279