Recombinant Probable double-stranded RNA-specific adenosine deaminase (adr-2)

中文名稱：

Recombinant Probable double-stranded RNA-specific adenosine deaminase(adr-2)
貨號：

CSB-YP635489CXY
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Probable double-stranded RNA-specific adenosine deaminase(adr-2)
貨號：

CSB-EP635489CXY
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Probable double-stranded RNA-specific adenosine deaminase(adr-2)
貨號：

CSB-EP635489CXY-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Probable double-stranded RNA-specific adenosine deaminase(adr-2)
貨號：

CSB-BP635489CXY
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Probable double-stranded RNA-specific adenosine deaminase(adr-2)
貨號：

CSB-MP635489CXY
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

adr-2
Uniprot No.：

Q22618
別名：

adr-2; T20H4.4Double-stranded RNA-specific adenosine deaminase adr-2; DRADA; EC 3.5.4.37
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區域：

1-495
氨基酸序列

MSVEEGMEVE LKSEKMDLDD NIPDFVKETV ERSGKNPMSL FSELYVHMTG NTPVFDFYNR NQPNGSMKFI CVVILNGERI EGNVKSKKKE AKVSCSLKGL EVVLKHVSEY VVPAVKFEEK TTFFEMLREH TYAKFYELCK NNALIYGFEK VIASVFLKIN GNLQIIALST GNKGLRGDKI VNDGTALIDC HAEILARRGL LRFLYSEVLK FSTEPPNSIF TKGKNALVLK PGISFHLFIN TAPCGVARID KKLKPGTSDD LQNSSRLRFK IDKGMGTVLG GASEFEAPQT FDGIMMGERM RTMSCSDKLL RANVLGVQGA ILSHFIDPIY YSSIAVAELN NADRLRKAVY SRAATFKPPA PFHVQDVEIG ECQVEDTEQS TSAAARSTIS SMNWNLADGN TEVVRTSDGM VHDKDMSGAD ITTPSRLCKK NMAELMITIC TLTKTSVDYP ISYEELKAGS QEYAAAKKSF ITWLRQKDLG IWQRKPREFQ MFTIN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. Acts primarily on non-coding regions of protein-coding genes including introns and untranslated regions (UTR). Required for normal chemotaxis. Edits the 3' UTR of clec-41 which is required for normal clec-41 expression and for chemotaxis. Plays a role in determining lifespan. Not required for RNA interference. Likely to play a role in determining whether a dsRNA enters the RNAi pathway.
基因功能參考文獻：
1. Intersecting the neural editome with adr-2 associated gene expression changes, revealed an edited mRNA, clec-41, whose neural expression is dependent on deamination by ADR-2. PMID: 28925356
亞細胞定位：

Nucleus. Cytoplasm.
數據庫鏈接：

KEGG: cel:CELE_T20H4.4

STRING: 6239.T20H4.4.1

UniGene: Cel.34304