Recombinant NEDD8 (ned-8)

中文名稱：

秀麗隱桿線蟲ned-8重組蛋白
貨號：

CSB-YP846313CXY
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲ned-8重組蛋白
貨號：

CSB-EP846313CXY
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲ned-8重組蛋白
貨號：

CSB-EP846313CXY-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲ned-8重組蛋白
貨號：

CSB-BP846313CXY
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲ned-8重組蛋白
貨號：

CSB-MP846313CXY
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ned-8
Uniprot No.：

Q93725
別名：

ned-8; F45H11.2; NEDD8; Neddylin; Protein NED-8; Ubiquitin-like protein Nedd8
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區域：

1-76
氨基酸序列

MLIKVKTLTG KEIELDIEPN DRVERIKEKV EEKEGIPPPQ QRLIFAGKQM NDDKTAADYK VLGGSVLHLV LALRGG
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex uba-3-ula-1 and linkage to the E2 enzyme ubc-12. Attachment of ned-8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
基因功能參考文獻：
1. DCN-1 directly bind Nedd8 and physically associate with cullins PMID: 15988528
亞細胞定位：

Nucleus. Cytoplasm. Note=Mainly nuclear during interphase, also cytoplasmic during interphase and mitosis.
蛋白家族：

Ubiquitin family
數據庫鏈接：

KEGG: cel:CELE_F45H11.2

STRING: 6239.F45H11.2

UniGene: Cel.18712