Recombinant Mouse Xin actin-binding repeat-containing protein 2 (Xirp2), partial

中文名稱：

小鼠Xirp2重組蛋白
貨號：

CSB-YP681049MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Xirp2重組蛋白
貨號：

CSB-EP681049MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Xirp2重組蛋白
貨號：

CSB-EP681049MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Xirp2重組蛋白
貨號：

CSB-BP681049MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Xirp2重組蛋白
貨號：

CSB-MP681049MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Xirp2
Uniprot No.：

Q4U4S6
別名：

Xirp2; Cmya3; Xin2; Xin actin-binding repeat-containing protein 2; Beta-xin; Cardiomyopathy-associated protein 3; Myogenic MEF2-activated Xin-related protein; Myomaxin; mXinbeta
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Protects actin filaments from depolymerization.
基因功能參考文獻：
1. XIRP2 is required for maintenance of stereocilia integrity. PMID: 25772365
2. XIRP2 is required for long-term maintenance of hair cell stereocilia, and its dysfunction causes hearing loss. PMID: 25653358
3. Data show that mXinbeta (CMYA3/XIRP2) but not mXinalpha ((CMYA1/XIRP1) was uniquely up-regulated during the redistribution of intercellular junction from the lateral membrane of cardiomyocytes to their termini. PMID: 23261932
4. The mXinbeta-null hearts showed upregulation of active Stat3 and downregulation of the activities of Rac1, insulin-like growth factor 1 receptor, protein kinase B, and extracellular signal-regulated kinases 1 and 2. PMID: 20360251
5. Reveal a novel MEF2A-Xirp2 pathway that functions downstream of Ang II signaling to modulate its pathological effects in the heart. PMID: 20093629
6. Deletion of mXin{beta} (Xirp2) leads to severe defects in postnatal cardiac development and lethality. mXin{beta} may play an essential role in N-Cadherin-mediated adhesion signaling and its cross talk signaling in the heart. PMID: 20360251
7. upregulation due to Ang II-induced myocardial damage and not to blood pressure elevation per se PMID: 16500513
8. Myomaxin functions directly downstream of MEF2A at the peripheral Z-disc complex in striated muscle potentially playing a role in regulating cytoarchitectural integrity PMID: 17046827
顯示更多

收起更多
亞細胞定位：

Cell junction. Note=Colocalizes with actin stress fibers.
蛋白家族：

Xin family
組織特異性：

Expression is restricted to heart and skeletal muscle. Present in intercalated disks of the heart and in the Z-disk region of skeletal muscle (at protein level).
數據庫鏈接：

KEGG: mmu:241431

STRING: 10090.ENSMUSP00000028410

UniGene: Mm.261043