Recombinant Mouse WD repeat-containing protein 19 (Wdr19), partial

中文名稱：

小鼠Wdr19重組蛋白
貨號：

CSB-YP666257MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Wdr19重組蛋白
貨號：

CSB-EP666257MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Wdr19重組蛋白
貨號：

CSB-EP666257MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Wdr19重組蛋白
貨號：

CSB-BP666257MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Wdr19重組蛋白
貨號：

CSB-MP666257MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Wdr19
Uniprot No.：

Q3UGF1
別名：

Wdr19; Ift144; Kiaa1638WD repeat-containing protein 19; Intraflagellar transport 144 homolog
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

As component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in cilia function and/or assembly. Essential for functional IFT-A assembly and ciliary entry of GPCRs. Associates with the BBSome complex to mediate ciliary transport.
基因功能參考文獻：
1. Mutations in Ift144, encoding a component of the trafficking machinery of primary cilia assembly, result in a range of embryo patterning defects, affecting the limbs, skeleton and neural system. Here, we show that embryos PMID: 25224227
2. study describes a mouse with an N-ethyl-N-nitrosourea -induced hypomorphic mutation in the gene encoding the IFT-A protein WDR19/IFT144; phenotypically, this mutant, twinkle-toes (Ift144twt), displays a number of features reminiscent of skeletal ciliopathies; Ift144 mutant embryos display a generalized ligand-independent expansion of hedgehog signalling PMID: 22228095
3. A weak allele of the IFT-A gene, Ift144, caused subtle defects in cilia structure and ectopic activation of the Shh pathway. PMID: 22689656
4. Expressed in normal and neoplastic prostate epithelium and is regulated by androgenic hormones. PMID: 12906858
亞細胞定位：

Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium, photoreceptor outer segment.
組織特異性：

Tissue-specific expression of isoforms. Expressed in the prostate, testis, epididymis, submaxillary and salivary glands. Expressed in ependymal cells lining brain ventricles (at protein level).
數據庫鏈接：

KEGG: mmu:213081

STRING: 10090.ENSMUSP00000038098

UniGene: Mm.127550