Recombinant Mouse Vacuolar fusion protein MON1 homolog A (Mon1a)

中文名稱：

小鼠Mon1a重組蛋白
貨號：

CSB-YP754247MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Mon1a重組蛋白
貨號：

CSB-EP754247MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Mon1a重組蛋白
貨號：

CSB-EP754247MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Mon1a重組蛋白
貨號：

CSB-BP754247MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Mon1a重組蛋白
貨號：

CSB-MP754247MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mon1a
Uniprot No.：

Q6PDG8
別名：

Mon1a; Vacuolar fusion protein MON1 homolog A
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區(qū)域：

1-556
氨基酸序列

MAADMQRKRS SECPEGTLAP SNGQSVERAE SPTPGLTQGT EPGAGQEGAM FVHTRSYEDL TELEDREASG DSPKECVGSP PPLATDMRQI SQDFSELSTQ LTGVARDLQE EMLPGSSEDW PEPQGAAGRG AATEPSQEGS TEGEEEDATE AWRLHQKHVF VLSEAGKPVY SRYGSEEALS STMGVMVALV SFLEADKNAI RSIHADGYKV VFVRRSPLVL VAVARTRQSA QELAQELLYI YYQILSLLTG AQLSHIFQQK QNYDLRRLLS GSERITDNLL QLMARDPSFL MGAARCLPLA AAVRDTVSAS LQQARARSLV FSILLAHNQL VALVRRKDQF LHPIDLHLLF NLISSSSSFR EGEAWTPVCL PKFNAAGFFH AHISYLEPDT DLCLLLISTD REDFFAVSDC RRRFQERLRK RGTHLALREA LRTPYYSVAQ VGIPDLRHFL YKSKSSGLFT SPEIEAPYSS EEEQERLLGL YQYLHSRAHN ASRPLKTIYY TGPNENLLAW VTGAFELYMC YSPLGTKASA VSAIHKLMRW IRKEEDRLFI LTPLTY
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes. Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form.
基因功能參考文獻：
1. Genetic interactions between Cp, Mon1a, and the Slc40a1 locus are involved in iron metabolism. PMID: 24121729
2. a role for Mon1a in anterograde trafficking through the secretory apparatus. PMID: 22665492
3. data identify SAND-1 (Mon1) and CCZ-1 (Ccz1) as critical and evolutionarily conserved components regulating the processing of ingested apoptotic cell corpses PMID: 20305638
4. Study presents evidence that Mon1a is involved in trafficking of ferroportin, the major mammalian iron exporter, to the surface of iron-recycling macrophages. PMID: 17632513
蛋白家族：

MON1/SAND family
組織特異性：

Widely expressed (at protein level).
數(shù)據(jù)庫鏈接：

KEGG: mmu:72825

STRING: 10090.ENSMUSP00000035202

UniGene: Mm.38037