Recombinant Mouse Uncharacterized protein C8orf4 homolog

中文名稱：

小鼠Tcim重組蛋白
貨號：

CSB-YP875244MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Tcim重組蛋白
貨號：

CSB-EP875244MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Tcim重組蛋白
貨號：

CSB-EP875244MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Tcim重組蛋白
貨號：

CSB-BP875244MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Tcim重組蛋白
貨號：

CSB-MP875244MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Tcim
Uniprot No.：

Q9D915
別名：

Tcim; Tc1; Transcriptional and immune response regulator
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-106
氨基酸序列

MKAKPSHQAT SMSSSLRVSP SIHGYHFDTA ARKKAVGNIF ENIDQESLQR LFRNSGDKKA EERAKIIFAI DQDLEEKTRA LMALKKRTKD KLLQFLKLRK YSIKVH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Seems to be involved in the regulation of cell growth an differentiation, may play different and opposite roles depending on the tissue or cell type. May enhance the WNT-CTNNB1 pathway by relieving antagonistic activity of CBY1. Enhances the proliferation of follicular dendritic cells. Plays a role in the mitogen-activated MAPK2/3 signaling pathway, positively regulates G1-to-S-phase transition of the cell cycle. In endothelial cells, enhances key inflammatory mediators and inflammatory response through the modulation of NF-kappaB transcriptional regulatory activity. Involved in the regulation of heat shock response, seems to play a positive feedback with HSF1 to modulate heat-shock downstream gene expression. Plays a role in the regulation of hematopoiesis even if the mechanisms are unknown. In cancers such as thyroid or lung cancer, it has been described as promoter of cell proliferation, G1-to-S-phase transition and inhibitor of apoptosis. However, it negatively regulates self-renewal of liver cancer cells via suppresion of NOTCH2 signaling.
基因功能參考文獻：
1. These data support that Tc1 is a novel regulator for adipose stem cells. PMID: 27775060
2. Tc1 mice express sleep-related phenotypes that are comparable with those seen in Down syndrome patients PMID: 25558895
3. TC1 was involved in the mitogen-activated ERK1/2 signaling pathway and positively regulated G(1)- to S-phase transition of the cell cycle.[TC1] PMID: 18959821
亞細胞定位：

Cytoplasm. Nucleus. Nucleus, nucleolus. Nucleus speckle.
組織特異性：

Expressed in liver, expression levels decrease in regenerating liver. In bone marrow, expressed in large progenitor-like cells, cells with ring-shaped nuclei and, at lower, levels in hematopietic stem cell-like cells with round nuclei (at protein level).
數據庫鏈接：

KEGG: mmu:69068

STRING: 10090.ENSMUSP00000058631

UniGene: Mm.25775