Recombinant Mouse UBX domain-containing protein 6 (Ubxn6)

中文名稱：

小鼠Ubxn6重組蛋白
貨號：

CSB-YP860843MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Ubxn6重組蛋白
貨號：

CSB-EP860843MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Ubxn6重組蛋白
貨號：

CSB-EP860843MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Ubxn6重組蛋白
貨號：

CSB-BP860843MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Ubxn6重組蛋白
貨號：

CSB-MP860843MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ubxn6
Uniprot No.：

Q99PL6
別名：

Ubxn6; Ubxd1; Ubxdc2; UBX domain-containing protein 6; UBX domain-containing protein 1
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-442
氨基酸序列

MKKFFQEIKA DIKFKSAGPG QKLTDSAGEK TTKGKSPQLA LRQPRQGPTD EAQMAAAAAL ARLEQKQPRA RGPTSQDSIR NQVRKELQAE ATSSNNPGAP GTNSVPEPKE EISPHLAVPG VFFICPLTGV TLRRDQRDAH IKQAILSHFS TDPVAASIMK IHTFNRDRDR VKLGVDTIAK YLDNIHLHPE EEKYQKIKLQ NKVFQERINC LEGSHEFFEA IGFKKVTLPV PDQEGQEEFY VLGEDARAQP QNLARHKQQL LDAEPVRATL DRQLRVFRPS ALASHFELPS DFFSLTAEEV KREQRLRTEA VERLSSLRTK AMREKEEQRE LRKYTYALVR VRLPDGCLLQ GTFYAREKLS ALFRFVREAL QNDWLPFELR ASGGQKLEEN EALALNECGL VPSALLTFSW DASVLEDIRA AGAEPAKSVL RPELLAAIEQ LS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes. As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.
基因功能參考文獻：
1. These results indicate that the outer membrane protein MCL1 is degraded by the VCP-UBXD1 complex and that the process is promoted by the presence of mutant Huntingtin. PMID: 27913212
亞細胞定位：

Cytoplasm. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Early endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein.
組織特異性：

Widely expressed (at protein level). Highest expression in brain (at protein level).
數據庫鏈接：

KEGG: mmu:66530

STRING: 10090.ENSMUSP00000019722

UniGene: Mm.28000