Recombinant Mouse Tripartite motif-containing protein 26 (Trim26)

中文名稱：

小鼠Trim26重組蛋白
貨號：

CSB-YP858789MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Trim26重組蛋白
貨號：

CSB-EP858789MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Trim26重組蛋白
貨號：

CSB-EP858789MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Trim26重組蛋白
貨號：

CSB-BP858789MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Trim26重組蛋白
貨號：

CSB-MP858789MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Trim26
Uniprot No.：

Q99PN3
別名：

Trim26; Znf173; Tripartite motif-containing protein 26; EC 2.3.2.27; Zinc finger protein 173
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-545
氨基酸序列

MAVSAPLRSL EEEVTCSICL DYLRDPVTID CGHVFCRSCT SDIRPISGNR PVCPLCKKPF KKENIRPVWQ LASLVENIER LKVDNGRQPG ELAREPQDMK LCERHQEKLH YYCEDDGKLL CVMCRESREH RPHTAVLVEK AALPHREKIL NHLNTLRRDR DKIQGFQAKG EADILAALTK LQEQRQYIVA EFKQGHQFLK KREQHLLDQL ATLEQLLTEG REKFKTRGVS ELDRLTLVIS ELEGKARQPA AELMQDVCTT QDTKDFANKY PRKKFWIGKA IPHMVKRKAG EFSDKLLSLQ RGLRQFQGKL LRDLEYKTVS VTLDPQSASG YLHLSEDWKC VTYTGQYQSD CLLPQQFDCE PGVLGSKGFT WGKVYWEVEL EREGWSEDEE EGEEEEEGEE EEEDEEVGYG DGYEDWETDE EDESLGEEEE EEEEEEEEVQ ESCMVGVAKD SVKRKGDLSL RPEDGVWALR LSPSGIWANT SPEAQLFPVL RPRRVGIALD YEGGTVTFTN AESQELIYTF TTTFTRRLVP FLWLKWPGAR LLLRP
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.
基因功能參考文獻(xiàn)：
1. Our findings delineate a novel mechanism for the termination of IRF3 activation in nucleus through TRIM26-mediated IRF3 ubiquitination and degradation. PMID: 25763818
亞細(xì)胞定位：

Cytoplasm. Nucleus.
蛋白家族：

TRIM/RBCC family
數(shù)據(jù)庫鏈接：

KEGG: mmu:22670

STRING: 10090.ENSMUSP00000060103

UniGene: Mm.34587