Recombinant Mouse Transcription factor Sp2 (Sp2)

中文名稱：

小鼠Sp2重組蛋白
貨號：

CSB-YP871966MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Sp2重組蛋白
貨號：

CSB-EP871966MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Sp2重組蛋白
貨號：

CSB-EP871966MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Sp2重組蛋白
貨號：

CSB-BP871966MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Sp2重組蛋白
貨號：

CSB-MP871966MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Sp2
Uniprot No.：

Q9D2H6
別名：

Sp2; Kiaa0048; Transcription factor Sp2
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-612
氨基酸序列

MSDPQMSMAA TAAVSPSDYL QPAAATTQDS QPSPLALLAA TCSKIGPPAV EAAVTPPAPP QPTPRKLVPI KPAPLPLSPC KNSFSILSSK GNILQIQGSQ LSTSYPGGQF VFAIQNPTLI NKGSRSNASI QYQVPQIQGN SSQTIQVQPS LTNQIQVIPG TNQAITTPST SGHKPVPIKP APVQKSSTTT TPVQSGANVV KLTGGGSNMT LTLPLNNLVN TSDIGGPAQL LTESPPTPLS KTNKKARKKS LPVSQPSVAV AEQVETVLIE TTADNIIQAG NNLLIVQSPG GGQPAVVQQV QVVPPKAEQQ QVVQIPQQAL RVVQAASATL PTVPQKPSQN FQIQTTEPTP TQVYIRTPSG EVQTVLVQDS PPATAATTST VTCNSPALRA PHLSGTSKKH SAAILRKERP LPKIAPAGSI ISLNAAQLAA AAQAMQTINI NGVQVQGVPV TITNTGGQQQ LTVQNVSGNN LTISGLSPTQ IQLQMEQALA GEAQPGEKRR RMACTCPNCK DGEKRSGEQG KKKHVCHIPD CGKTFRKTSL LRAHVRLHTG ERPFVCNWFF CGKRFTRSDE LQRHARTHTG DKRFECAQCQ KRFMRSDHLT KHYKTHLGTK GL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.
基因功能參考文獻：
1. SP2 as important factor responsible for higher Cd14 expression and reduced IBD susceptibility mediated by the C3Bir allele. PMID: 27191968
2. Our results unveil strikingly different recruitment mechanisms of Sp1/Sp2/Sp3 transcription factor members uncovering an unexpected layer of complexity in their binding to chromatin in vivo. PMID: 25793500
3. Sp2 deletion disrupts neurogenesis in the embryonic and postnatal brain. PMID: 23293287
4. Specificity protein 2 (Sp2) is essential for mouse development and autonomous proliferation of mouse embryonic fibroblasts PMID: 20221402
5. Overexpression of transcription factor sp2 inhibits epidermal differentiation and increases susceptibility to wound- and carcinogen-induced tumorigenesis. PMID: 20959487
6. mouse Sp2 transcription yields alternatively spliced and sub-genomic mRNAs in a tissue- and cell-type-specific fashion PMID: 20353838
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亞細胞定位：

Nucleus.
蛋白家族：

Sp1 C2H2-type zinc-finger protein family
數據庫鏈接：

KEGG: mmu:78912

STRING: 10090.ENSMUSP00000103252

UniGene: Mm.491183