Recombinant Mouse Threonine aspartase 1 (Tasp1)

中文名稱：

小鼠Tasp1重組蛋白
貨號：

CSB-YP837122MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Tasp1重組蛋白
貨號：

CSB-EP837122MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Tasp1重組蛋白
貨號：

CSB-EP837122MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Tasp1重組蛋白
貨號：

CSB-BP837122MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Tasp1重組蛋白
貨號：

CSB-MP837122MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Tasp1
Uniprot No.：

Q8R1G1
別名：

Tasp1; Threonine aspartase 1; Taspase-1; EC 3.4.25.-) [Cleaved into: Threonine aspartase subunit alpha; Threonine aspartase subunit beta]
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區(qū)域：

1-233
氨基酸序列

MIMEKGMNSG EGLPSRSSQA SAAKVTVKEL ETQQPCKEKR GGFVLVHAGA GYHSESKAKE YKHVCKRACQ KAIEKLQAGA LATDAVAAAL VELEDSPFTN AGIGSNLNLL GEIECDASIM DGKSLNFGAV GALSGIKNPV SVAHRLLCEG QKGKLSAGRI PPCFLVGEGA YRWAVDHGIP SCPPSTMTTR FSLAAFKRNK RKLELAERVE TDFIQLKRRR QSSAKENDSG TLD
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Protease responsible for KMT2A/MLL1 and KMT2D/MLL2 processing and activation. Through substrate activation, it controls the expression of HOXA genes, and the expression of key cell cycle regulators including CCNA1, CCNB1, CCNE1 and CDKN2A.
基因功能參考文獻：
1. Taspase1 deficiency disrupts the expression of cyclins and proliferation of HER2+ breast cancer cells. PMID: 25267403
2. TFIIA is the principal TASP1 substrate that orchestrates craniofacial morphogenesis. PMID: 25664857
3. This paper describes the quintessential function of Taspase1 in orchestrating cell cycle progression. PMID: 16951254
蛋白家族：

Ntn-hydrolase family
數(shù)據(jù)庫鏈接：

KEGG: mmu:75812

STRING: 10090.ENSMUSP00000039546

UniGene: Mm.293449