Recombinant Mouse Thioredoxin domain-containing protein 3 (Txndc3)

中文名稱：

小鼠Nme8重組蛋白
貨號：

CSB-YP765139MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Nme8重組蛋白
貨號：

CSB-EP765139MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Nme8重組蛋白
貨號：

CSB-EP765139MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Nme8重組蛋白
貨號：

CSB-BP765139MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Nme8重組蛋白
貨號：

CSB-MP765139MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nme8
Uniprot No.：

Q715T0
別名：

Nme8; Sptrx2; Txndc3; Thioredoxin domain-containing protein 3; NME/NM23 family member 8; Spermatid-specific thioredoxin-2; Sptrx-2
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-586
氨基酸序列

MASKKREVQL QSVVNSQNLW DEMLLNKGLT VIDVYQAWCG PCKAVQSLFR KLKNELNEDE ILHFVVAEAD NIVTLQPFRD KCEPVFLFSL NGKIIAKIQG ANAPLINRKV ITLIDEERKI VAGEMDRPQY VEIPLVDAID EEYGEVQYES AAEVYNMAII KPDAVLMRKN IEVREKIAKE GFVIEIQENL ILPEEVVREF YTHIADQPDF EEFVVSMTNG LSCVLIVSQE DSEVIQEETL PQTDTEEEPG VLEEPHVRFA PVMIKKKRDS LQEYMDRQHM SDYCDVEDDA VKVSKLIDIL FPDFKTMKST NVQTTLALLH PDICEEEKDD VLNVIHNEGF TILMQRQIVL SEEEARTVCK IHENEEYFDN LIGHMTSNHS YVLALRRENG VEYWKTLIGP KTIEEAYASH PQSLCVQFAS GNFPTNQFYG SSSKAAAEKE IAHFFPPQST LALIKPHVTH KERMEILKTI KEAGFELTLM KEMHLTPEHA NKIYFKITGK DFYKNVLEVL SLGMSLVMVL TKWNAVAEWR RMVGPVDPEE AKLLSPESLR AKYGLDILRN AVHGASNFSE ASEIISNVFT EGNPEN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds.
基因功能參考文獻：
1. Txndc2 and Txndc3 are critically important in protecting spermatozoa against the increases in oxidative stress associated with paternal age. PMID: 23707457
2. data indicate that spermatid-specific thioredoxin-2 incorporation into the sperm fibrous sheath(FS) lags well behind FS assembly, suggesting it is required during the final stages of sperm tail maturation PMID: 12909633
亞細胞定位：

Cytoplasm.
蛋白家族：

NDK family
組織特異性：

Testis-specific. Expressed mainly in round spermatids.
數據庫鏈接：

KEGG: mmu:73412

STRING: 10090.ENSMUSP00000089358

UniGene: Mm.279939