Recombinant Mouse Sodium/bile acid cotransporter 4 (Slc10a4), partial

中文名稱：

小鼠Slc10a4重組蛋白
貨號：

CSB-YP662337MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Slc10a4重組蛋白
貨號：

CSB-EP662337MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Slc10a4重組蛋白
貨號：

CSB-EP662337MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Slc10a4重組蛋白
貨號：

CSB-BP662337MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Slc10a4重組蛋白
貨號：

CSB-MP662337MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Slc10a4
Uniprot No.：

Q3UEZ8
別名：

Slc10a4Sodium/bile acid cotransporter 4; Na(+)/bile acid cotransporter 4; Solute carrier family 10 member 4
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transporter for bile acids.
基因功能參考文獻：
1. In summary, SLC10A4 acts as a regulator of degranulation in vitro and of mast cell-related reactions in vivo. PMID: 28439090
2. Study indicates that loss of SLC10A4 protein results in neurotransmitter imbalance and cognitive impairment in null mice PMID: 27001174
3. SLC10A4 failed to show transport activity for a series of neurotransmitters and neuromodulators, indicating that SLC10A4 does not seem to represent a typical neurotransmitter transporter such as DAT, SERT, CHT1 or VMAT2 PMID: 26084360
4. Results demonstrate that SLC10A4 is a vesicular monoaminergic and cholinergic associated transporter that is important for dopamine homeostasis and neuromodulation in vivo PMID: 25176177
5. Results suggest that VAAT modulates neuromuscular junction transmission efficiency and, as such, may represent a novel target for treatment of disorders affecting motor neurons PMID: 25410831
6. absence of the recently discovered synaptic vesicle protein Slc10a4 results in increased sensitivity to cholinergic stimulation PMID: 23022458
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亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Bile acid:sodium symporter (BASS) (TC 2.A.28) family
組織特異性：

Highest expression in the brain and significantly above background levels in the eye, prostate, and whole embryo tissue preparations.
數據庫鏈接：

KEGG: mmu:231290

STRING: 10090.ENSMUSP00000031127

UniGene: Mm.491387