Recombinant Mouse Selenocysteine-specific elongation factor (Eefsec)

中文名稱：

小鼠Eefsec重組蛋白
貨號：

CSB-YP872831MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Eefsec重組蛋白
貨號：

CSB-EP872831MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Eefsec重組蛋白
貨號：

CSB-EP872831MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Eefsec重組蛋白
貨號：

CSB-BP872831MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Eefsec重組蛋白
貨號：

CSB-MP872831MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Eefsec
Uniprot No.：

Q9JHW4
別名：

Eefsec; Selb; Selenocysteine-specific elongation factor; Elongation factor sec; Eukaryotic elongation factor; selenocysteine-tRNA-specific; mSelB
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-583
氨基酸序列

MAGRRVNVNV GVLGHIDSGK TALARALSTT ASTAAFDKQP QSRERGITLD LGFSCFVVPL PGAEPGSSDT LLQVTLVDCP GHASLIRTII GGAQIIDLMM LVIDVTKGMQ TQSAECLVIG QIACQKLVVV LNKIDLLAEG KRQAAIDKMT KKMQKTLENT KFRGAPIIPV AAKPGGPEAP ETEAPQGISE LIELLKSQIS IPTRDPSGPF LMSVDHCFSI KGQGTVMTGT ILSGTISLGD SVEIPALKVV KKVKSMQMFH TPVTSAMQGD RLGICVTQFD PKLLERGLVC APESLHTVHA ALISVEKIPY FRGPLQTKAK FHITVGHETV MGRTLFFSPA PDSFDLEPVL DSFDLSREYL FQEQYLCKDS MPTATEGDDE ADPKAGHAPG GHCPRQQWAL VEFEKPVTCP RLCLVIGSRL DADIHTNTCR LAFHGVLLQG LEDKNYIESF LPALRVYKLK HKHGLVERVM DDYSVIGRSL FKKETNIQLF VGLKVQLSTG EQGIIDSAFG QSGKFKIHIP GGLSPESKKI LTPTLKKRSR AGRGETTKPE EGTERPEPIQ PVTLNLSFKR YVFDTQKRMV QTP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.
基因功能參考文獻：
1. This study examined the subcellular localization of eEFSec in the context of altered Selenocysteine incorporation to demonstrate that reduced selenoprotein production does not correlate with changes in the nuclear localization of eEFSec. PMID: 27802322
2. SBP2/SECIS complex activates eEFSec by directing functional interactions between Domain IV and the ribosome to promote Sec-tRNA(Sec) binding and accommodation into the ribosomal A-site PMID: 22992746
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, SelB subfamily
數據庫鏈接：

KEGG: mmu:65967

STRING: 10090.ENSMUSP00000131207

UniGene: Mm.333237