Recombinant Mouse Rho GTPase-activating protein 36 (Arhgap36)

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 36(Arhgap36)
貨號：

CSB-YP532839MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 36(Arhgap36)
貨號：

CSB-EP532839MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 36(Arhgap36)
貨號：

CSB-EP532839MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 36(Arhgap36)
貨號：

CSB-BP532839MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 36(Arhgap36)
貨號：

CSB-MP532839MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Arhgap36
Uniprot No.：

B1AUC7
別名：

Arhgap36; Rho GTPase-activating protein 36
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-590
氨基酸序列

MAWMLDCLFA SAFEPRPRRV SVLGGAPGQN SDRSMDMVSI HSLSELERLK LQETAYHELV ARHFLSEFKP DRALPTDRPN TLEKWFLMLR GQDRAASLKT FGIRLEEVLV NELTRRKQRE LTPTMQVEDI NGSTGRRRRG NVVQRMLGRM RRFFSRRRNE PTLPREFTRR GRRGAVSADS ADELENGALL LQILQLSQLS SPIGQRLLGS KRKMSLNPIA QQIPQIVETC CKFIEKHGLS SVGIFTIEYS LRRVLELREL FDKGLDIVLD DSVNVHDVAE LLKEFFREMK DPLLPDDLYM SFLLTATLKP KDQVSALQLL VYLMPPCHSD TLERLLKALH KITENCEDSI GVDGQLVPGN RMTSTNLALV FGTALLKKGK LANKESRKTK LGIDHYVASV NVVRAMIDNW DILFQVPPHI QKEVAKRVWK SSPEALDFIR RRNLRKIQSA RIKMEEDALL SDPVENSAEA QAAILAQSQP FDEDPEGAPD VHEVLNDNLN YDFEDESDFE DQDHLDLAEV PYLDVIPNNE DTDSDADVIP GPSEEPAVPA STAGSPDKEE GAAGNPPNAD RPLPRVPQGK KGKFATRFFP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
基因功能參考文獻：
1. a new mechanism of Gli transcription factor activation and implicate ARHGAP36 dysregulation in the onset and/or progression of GLI-dependent cancers. PMID: 25024229
2. Arhgap36 acts in a Smoothened-independent manner to promote the activation of full-length Gli proteins and induces the accumulation of Gli proteins in the primary cilium. Its ability to induce Gli-dependent transcription requires kinesin family member 3a and intraflagellar transport protein 88, proteins that are essential for ciliogenesis. Arhgap36 functionally and biochemically interacts with Suppressor of Fused. PMID: 25024229
數據庫鏈接：

KEGG: mmu:75404

STRING: 10090.ENSMUSP00000110554

UniGene: Mm.44305