Recombinant Mouse Rho GTPase-activating protein 22 (Arhgap22)

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 22(Arhgap22)
貨號：

CSB-YP805918MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 22(Arhgap22)
貨號：

CSB-EP805918MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 22(Arhgap22)
貨號：

CSB-EP805918MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 22(Arhgap22)
貨號：

CSB-BP805918MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 22(Arhgap22)
貨號：

CSB-MP805918MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Arhgap22
Uniprot No.：

Q8BL80
別名：

Arhgap22; Rho GTPase-activating protein 22; Rho-type GTPase-activating protein 22; p68RacGAP
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-702
氨基酸序列

MLPTASSKRR TFAARYFTRS KSLVMGEQSR SPGRPLVPHK LGPVLKAGWL RKQRSIMKNW QQRWFVLRGD QLFYYKDKDE SKPQGFISLQ GTQVTELLPD PEDPGKHLFE ITPGGATERE KVPANPEALL LMASSQRDME DWVQAIRRVI WAPLGRGIFG QRLEDTVHHE RKFGPRLAPL LVEQCVDFIR ERGLSEEGLF RMPGQANLVR DLQDSFDCGE KPLFDSTTDV HTVASLLKLY LRELPEPVIP FARYEDFLSC AQLLTKDEGE GTVELAKQVS NLPQANYNLL RYICKFLDEV QAHSDVNKMS VQNLATVFGP NILRPQIEDP VTIMEGTSLV QHLMTVLIRK HGQLFAATSL EEPASPHGTV EWGSEEVTRD HRGEPGSPGL PTHRTSSLDG PAAAVLSRTS PPRLGSQTGP AATSPGKKMH TLPVWKSSFR QQGSRSESPK GVNSSLEVPI ISSGGNWLIN GLSSLRSHRR ASSGDRLKDT GSAQRLSTYD NVPPSSQFSS TASVASTSWS VASSSREASV SSCTACRASN SSACSSLHTE WALEPSPLPS SSEGHQSPDL GHSLDEPCVG SGSSEPNDPG SPTQAHVRRC RALQGQVAEL RAELCQQRTE YKRSLKSIEE GSADLRKQMS RLEEELDQER KKYAMLEIKL RNSERAREDA ERRNQLLQRE MEEFFSTLGS LTTGTKGSRA PE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter.
基因功能參考文獻：
1. a multifunctional regulatory protein with Rac1-specific GTPase-activating activity; regulates transcriptional activity of the endothelin-1 promoter; involved in the signal transduction pathway regulating endothelial cell capillary tube formation PMID: 14966113
亞細胞定位：

Cytoplasm. Nucleus. Note=Mainly cytoplasmic. Some fraction is nuclear.
組織特異性：

Predominantly present in endothelial cells (at protein level).
數據庫鏈接：

KEGG: mmu:239027

STRING: 10090.ENSMUSP00000107587

UniGene: Mm.318350