Recombinant Mouse Rho GTPase-activating protein 10 (Arhgap10)

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 10(Arhgap10)
貨號：

CSB-YP757866MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 10(Arhgap10)
貨號：

CSB-EP757866MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 10(Arhgap10)
貨號：

CSB-EP757866MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 10(Arhgap10)
貨號：

CSB-BP757866MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Rho GTPase-activating protein 10(Arhgap10)
貨號：

CSB-MP757866MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Arhgap10
Uniprot No.：

Q6Y5D8
別名：

Arhgap10; Rho GTPase-activating protein 10; PH and SH3 domain-containing rhoGAP protein; PS-GAP; PSGAP; Rho-type GTPase-activating protein 10
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-786
氨基酸序列

MGLQPLEFSD CYLDSPWFRE RIRAHEAELE RTNKFIKELI KDGKNLISAT KSLSAAQRKF AHSLRDFKFE FIGDAETDDE RCIDASLREF SNFLKNLEEQ REIMALSVTE TLIKPLEKFR KEQLGAVKEE KKKFDKETEK NYSLIDKHLT LSARKKDSHL QEADLQVEQN RQHFYELSLE YVCKLQEIQE RKKFEFVEPM LSFFQGMFTF YHQGHELSKD FNHYKMELQI NIQNTRNRFE GTRSEVEELM NKIRQNPKDQ KRASQFTAEG YLYVQEKRPA PFGSSWVKHY CMYRKTAKKF NMIPFEHRSG GKLGDGEAFF LKECTKRHMD STDRRFCFDI EAADRPGVPL TVQAFSEEER KQWLEALGGK EALFHTFNRA IVPRPEGGAQ LDKMGFTILR KCISAVETRG INDQGLYRVV GVSSKVQRLL SMLMDVKMCN ELDLENSADW EVKTVTSALK QYLRSLPEPL MTYELHRDFI VPAKSGSPES RVNAIHFLVH KLPEKNKEML DILVKHLTNV SSHSKQNLMT VANLGVVFGP TLMRPQEETV AAIMDLKFQN IVVEILIENH EKIFRTSPDT TFAEPTCLSA SPPNAPPRQS KRQGQRTKRP VAVYNLCLEL EEGDSPSPLK EDPPSSSQDS LSTPSPTTSA AHGPPGLDGN HLAADGGSCG DATATTPSQT RPSMVQWLNM QSPTTPSSNP AGTPPSPRMS PFPLSPAASI VDKLPECVIN RKARAVYPCE AEHSSELSFE IGAIFEDVQT SREPGWLEGT LNGKRGLIPQ NYVKLL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.
基因功能參考文獻：
1. ARHGAP10 may serve as a tumor suppressor through inactivating Cdc42, as well as inhibiting cell cycle, replication and BER pathways. PMID: 27010858
亞細胞定位：

Cytoplasm. Cytoplasm, perinuclear region. Cell membrane. Note=Association to cell membrane is dependent on PH domain.
組織特異性：

High levels of expression in brain, testes, liver, heart and kidney.
數據庫鏈接：

KEGG: mmu:78514

STRING: 10090.ENSMUSP00000075658

UniGene: Mm.165974