Recombinant Mouse Retrotransposon-derived protein PEG10 (Peg10), partial

中文名稱：

小鼠Peg10重組蛋白
貨號：

CSB-YP756013MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Peg10重組蛋白
貨號：

CSB-EP756013MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Peg10重組蛋白
貨號：

CSB-EP756013MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Peg10重組蛋白
貨號：

CSB-BP756013MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Peg10重組蛋白
貨號：

CSB-MP756013MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Peg10
Uniprot No.：

Q7TN75
別名：

Peg10; Edr; Mar2; Mart2; Mef3l1; Rgag3Retrotransposon-derived protein PEG10; Embryonal carcinoma differentiation regulated protein; Mammalian retrotransposon-derived protein 2; Myelin expression factor 3; MyEF-3; Myelin expression factor 3-like protein 1; MEF3-like protein 1; Paternally expressed gene 10 protein; Retrotransposon gag domain-containing protein 3; Retrotransposon-derived gag-like polyprotein; Ty3/Gypsy-like protein
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May have a role in cell growth promotion, apoptotic resistance and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ACVRL1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ACVRL1. Involved at the immediate early stage of adipocyte differentiation. May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter.
基因功能參考文獻：
1. Loss of DNA methylation at the Peg10 imprinted gDMD associated with decreased embryonic viability and decreased labyrinthine volume. PMID: 26241757
2. Knockdown of Syncytin-A demonstrated a functional regulation of cell-cell fusion, where knockdown of Peg10 showed no involvement in cell fusion PMID: 23807393
3. Characterization of a RNA pseudoknot as a frameshift signal for Edr programmed -1 ribosomal frameshifting. PMID: 15767280
4. It is a retrotransposon-derived imprinted gene and plays a essential role in placental formation.(review) PMID: 21089286
5. Peg10 gene is imprinted, with preferential expression from the paternal allele, and its deletion results in early embryonic lethality. PMID: 16341224
6. Results indicate that the induction of the imprinted gene paternally expressed 10 (PEG10) may play an important role during liver regeneration or carcinogenesis of the hepatocyte. PMID: 14576465
7. These findings strongly indicate that peg10 plays a crucial role at the immediate early stage of adipocyte differentiation. PMID: 17707377
8. the ORF1-2 protein of PEG10, synthesized utilizing the most efficient -1 frameshift mechanism yet documented in vivo, will have an essential function that is intrinsic to the importance of PEG10 in mammals PMID: 17942406
9. Programmed -1 ribosomal frameshifting in mouse and human Peg10 genes. PMID: 15767280
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亞細胞定位：

Nucleus. Cytoplasm.
組織特異性：

Expressed in brain and testis. Expressed during the early process of adipocyte differentiation. Expressed weakly in mammary gland but strongly in breast carcinomas of a c-MCY-driven transgenic model.
數據庫鏈接：

KEGG: mmu:170676

STRING: 10090.ENSMUSP00000134963

UniGene: Mm.320575