Recombinant Mouse Regulating synaptic membrane exocytosis protein 2 (Rims2), partial

中文名稱：

小鼠Rims2重組蛋白
貨號：

CSB-YP863653MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Rims2重組蛋白
貨號：

CSB-EP863653MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Rims2重組蛋白
貨號：

CSB-EP863653MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Rims2重組蛋白
貨號：

CSB-BP863653MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Rims2重組蛋白
貨號：

CSB-MP863653MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rims2
Uniprot No.：

Q9EQZ7
別名：

Rims2; Rab3ip2; Rim2; Regulating synaptic membrane exocytosis protein 2; Rab-3-interacting molecule 2; RIM 2; Rab-3-interacting protein 2
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes.
基因功能參考文獻：
1. RIM2alpha and RIM2beta promote a large complement of synaptic CaV1.3 Ca(2+) channels at inner hair cell presynaptic active zones and are required for normal hearing. PMID: 26034270
2. Rim2alpha is involved in Zona Pellucida dependent signaling. PMID: 25240052
3. Rim2alpha determines docking and priming states in insulin granule exocytosis depending on its interacting partner, Rab3A or Munc13-1, respectively. PMID: 20674857
4. Alternative splicing in the Rab-binding domain of Rim2 regulates Rab3A binding activity. PMID: 15330860
5. Cyclic AMP rescue of priming defects caused by Munc13-1 deficiency signaling pathways requires downstream Munc13-1-Rim2 interaction. PMID: 17639022
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亞細胞定位：

Cell junction, synapse, synaptosome.
組織特異性：

Detected in testis, pituitary and an insulinoma cell line. Detected at low levels in cerebellar cortex.
數據庫鏈接：

KEGG: mmu:116838

UniGene: Mm.309296