Recombinant Mouse Ras-related protein Rab-43 (Rab43)

中文名稱：

小鼠Rab43重組蛋白
貨號：

CSB-YP806536MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Rab43重組蛋白
貨號：

CSB-EP806536MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Rab43重組蛋白
貨號：

CSB-EP806536MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Rab43重組蛋白
貨號：

CSB-BP806536MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Rab43重組蛋白
貨號：

CSB-MP806536MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rab43
Uniprot No.：

Q8CG50
別名：

Rab43; Ras-related protein Rab-43
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-210
氨基酸序列

MAGPGPGDQD EHYDFLFKLV LVGDASVGKT CVVQRFKTGA FSARQGSTIG VDFTMKTLEI QGKRVKLQIW DTAGQERFRT ITQSYYRSAN GAILAYDISK RSTFLSVPHW IEDVRKYAGS NIVQLLIGNK SDLADFREVP LAEAQSLAEH YDILCAIETS AKDSSNVEEA FTRVATELIM RHGGPMFSEK NTDHIQLDSK DIAESWGCGC
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium.
基因功能參考文獻：
1. These results suggest that RAB43 provides a specialized activity used in cross-presentation selectively by CD8alpha(+) DCs but not other antigen-presenting cells. PMID: 27899443
亞細胞定位：

Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network.
蛋白家族：

Small GTPase superfamily, Rab family
數據庫鏈接：

KEGG: mmu:69834

STRING: 10090.ENSMUSP00000077716

UniGene: Mm.37380