Recombinant Mouse Rab-interacting lysosomal protein (Rilp)

中文名稱：

小鼠Rilp重組蛋白
貨號：

CSB-YP705858MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Rilp重組蛋白
貨號：

CSB-EP705858MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Rilp重組蛋白
貨號：

CSB-EP705858MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Rilp重組蛋白
貨號：

CSB-BP705858MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Rilp重組蛋白
貨號：

CSB-MP705858MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rilp
Uniprot No.：

Q5ND29
別名：

Rilp; Rab-interacting lysosomal protein
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-369
氨基酸序列

MEPRRAAPRL PSQASSSVGA GSAAELVYHL AGALGTELQG LARRFGPDAA AGLVPLVVRA LELLEKAAVG PAPDSLQVSA QQAEVELRRL REENQRLRQE LGSGPQEERA LLRQLKEVTD RQRDELRAHN RDLQRRSQET EALQEQLQRL LLINSELRHK LAAVQTQLRA AQDRERERQI AQDGSSQLAK EQSLEPDAAT SDDPVDTQKQ PGNLPEAVQC GFSREELKQI LQERNELKAN VFLLKEELAY FQRELLTDHR VPGLLLEAMK VAVKKQRRKI KAKMLGTPEE AESSEDEDGS WLLLSNDKED VPLVPESRIQ NFFGLWYRGE TEAPEAETSN PASSSLQKGE ETPQQPHLQP VNSPPAPNS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes.
基因功能參考文獻：
1. The up-regulation of Rab11, Rab7, or RILP, but not its truncated form RILP-C33, rescued LAMP2A-defective trafficking in cystinosis, whereas dominant-negative Rab11 or Rab7 impaired LAMP2A trafficking. PMID: 28465352
2. A new mechanism by which the dynein-dynactin motor complex recognizes Mreg on mature melanosomes is revealed through interaction with RILP and is involved in the centripetal movement of melanosomes. PMID: 22275436
3. CD63, but not RILP, is recruited to the phagosomes in macrophages expressing the dominant negative form of Rab7. PMID: 20236428
亞細胞定位：

Late endosome membrane. Lysosome membrane. Cytoplasmic vesicle, phagosome membrane.
數據庫鏈接：

KEGG: mmu:280408

STRING: 10090.ENSMUSP00000037238

UniGene: Mm.41416