Recombinant Mouse Protein naked cuticle homolog 1 (Nkd1)

中文名稱：

小鼠Nkd1重組蛋白
貨號：

CSB-YP859149MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Nkd1重組蛋白
貨號：

CSB-EP859149MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Nkd1重組蛋白
貨號：

CSB-EP859149MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Nkd1重組蛋白
貨號：

CSB-BP859149MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Nkd1重組蛋白
貨號：

CSB-MP859149MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nkd1
Uniprot No.：

Q99MH6
別名：

Nkd1; Protein naked cuticle homolog 1; Naked-1; mNkd; mNkd1
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-471
氨基酸序列

GKLHSKPAA VCKRRESPEG DSFAVSAAWA RKGIEEWIGR QRCPGSVSGP RQLRLAGTVG RGTRELVGDT SREALGEEDE DDFPLEVALP PEKIDSLGSG DEKRMERLSE PGQASKKQLK FEELQCDVSV EEDSRQEWTF TLYDFDNNGK VTREDITSLL HTIYEVVDSS VNHSPTSSKT LRVKLTVAPD GSQSKRSVLF NHTDLQSTRP RADTKPAEEL RGWEKKQRAP LRFQGDSHLE QPDCYHHCVD ENIERRNHYL DLAGIENYTS QFGPGSPSVA QKSELPPRIS NPTRSRSHEP EAAHIPHRRP QGVDPGSFHL LDTPFAKASE LQQRLRGTQD GSKHFVRSPK AQGKNMGMGH GARGARSKPP LVPTTHTVSP SAHLATSPAL LPTLAPLGHK KHKHRAKESQ ASCRGLQGPL AAGGSTVMGR EQVRELPAVV VYESQAGQAV QRHEHHHHHE HHHHYHHFYQ P
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for spermatogenesis.
基因功能參考文獻：
1. The NKD1/Rac1 feedback loop regulates the invasion and migration ability of hepatocellular carcinoma cells. PMID: 27231134
2. deletion of the EF-hand from Nkd1 reduces the number of the elongating spermatids at haploid stage PMID: 15546883
3. Viable mice were obtained with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2. PMID: 17438140
亞細胞定位：

Cell membrane. Cytoplasm.
蛋白家族：

NKD family
組織特異性：

Highly expressed in lung. Also expressed in brain, heart, kidney, liver, skin, stomach and testis. Within the testis expression is found in the seminiferous epithelium and round and elongating spermatids.
數據庫鏈接：

KEGG: mmu:93960

STRING: 10090.ENSMUSP00000034086

UniGene: Mm.30219