Recombinant Mouse Protein ZNF365 (Znf365)

中文名稱：

小鼠Znf365重組蛋白
貨號：

CSB-YP804777MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Znf365重組蛋白
貨號：

CSB-EP804777MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Znf365重組蛋白
貨號：

CSB-EP804777MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Znf365重組蛋白
貨號：

CSB-BP804777MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Znf365重組蛋白
貨號：

CSB-MP804777MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Znf365
Uniprot No.：

Q8BG89
別名：

Znf365; Dbz; Kiaa0844; Zfp365Protein ZNF365; DISC1-binding zinc-finger protein; Su48
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-408
氨基酸序列

MQQTTFEESR YHWQDSLENV AVCLPFRCPR CGDHTRFRSL SSLRAHLEFS HSYEERTLLT KCSLLPSLKD TELLRSSELP KQGKVLRGHA KVTKQKSSYV NLYSISHGHS KDTKPFEMVA ERPVSYVQTY TAVDIRADSL DAPCASPGLP TQDTKAAFEA HVREKFNRMV EAVDRTIEKR IDKLTKELAQ KTAELLEVRA AFAQLTQKKQ EVQRRERALN KQVDVAVEMI AVLKQRLTES EEELLRKEEE VVTFNHFLEA AAEKEVQGKA RLQDFIENLL QRVELAEKQL EYYQSQQASG FSCDTSEHML TDIPSNRKPR CLSRGHQHSV CNHPEMRAHF HLKGRSYLKK AKDERAGMQP AKAIHEPAES PREFFRPAKK GEHLGLSRKG NFRPKMAKKK PTAIVNII
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Contributes to genomic stability by preventing telomere dysfunction. Involved in the morphogenesis of basket cells in the somatosensory cortex during embryogenesis. Involved in the positive regulation of oligodendrocyte differentiation during postnatal growth. Involved in dendritic arborization, morphogenesis of spine density dendrite, and establishment of postsynaptic dendrite density in cortical pyramidal neurons. Involved in the regulation of neurogenesis. Negatively regulates neurite outgrowth. Involved in homologous recombination (HR) repair pathway. Required for proper resolution of DNA double-strand breaks (DSBs) by HR. Is required for recovery of stalled replication forks, and directly contributes to genomic stability. Interacts with PARP1 and mediates MRE11-dependent DNA end resection during replication fork recovery.
基因功能參考文獻：
1. The oligodendrocyte differentiation in rodents was determined to be regulated by DBZ. PMID: 24481677
2. These findings show that DBZ is involved in the morphogenesis of basket cells. PMID: 23912123
3. These results suggest an homologous recombination repair-dependent function of ZNF365 in preventing genomic instability. PMID: 23966166
亞細胞定位：

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
組織特異性：

Detected in several tissues, with highest levels in brain. Also expressed during embryonic development. Expressed in cerebral cortex, hippocampus, striatum, inferior colliculus and thalamus.
數據庫鏈接：

KEGG: mmu:216049

STRING: 10090.ENSMUSP00000067197

UniGene: Mm.268346