Recombinant Mouse Protein MTO1 homolog, mitochondrial (Mto1)

中文名稱：

小鼠Mto1重組蛋白
貨號(hào)：

CSB-YP846064MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

小鼠Mto1重組蛋白
貨號(hào)：

CSB-EP846064MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

小鼠Mto1重組蛋白
貨號(hào)：

CSB-EP846064MO-B
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Mto1重組蛋白
貨號(hào)：

CSB-BP846064MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

小鼠Mto1重組蛋白
貨號(hào)：

CSB-MP846064MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mto1
Uniprot No.：

Q923Z3
別名：

Mto1; Protein MTO1 homolog; mitochondrial
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

26-669
氨基酸序列

SDSAA PCTPHFDVVV IGGGHAGTEA AAAAARCGSR TLLLTHRVDT IGQMSCNPSF GGIGKGHLMR EVDALDGLCS RICDQSGIHY KVLNRRKGPA VWGLRAQIDR KLYKQNMQKE ILSTPLLTVQ KGAVEDLVLA EPEPGYPGKS RVRGVVLADG STIYAESVIL TTGTFLRGMI IIGLEMHPAG RLGDQPSIGL AQTLEKLGFM VGRLKTGTPP RLGKESINFS ILNKHTPDDP SIPFSFLSDS VWIKPEDQLP CYLTHTNPRV DAIVLENLHL NSHVQETTKG PRYCPSIESK VLRFPNRLHQ VWLEPEGMDS DLIYPQGLSV TLPAELQEKM ITCIRGLEKA KMVHPGYGVQ YDYLDPRQIS PSLETHLVQR LFFAGQINGT TGYEEAAAQG VIAGINASLR VSRKPPFVVS RTEGYIGVLI DDLTTLGTSE PYRMFTSRVE FRLSLRPDNA DTRLTFRAHK EAGCVSSQRF ERALWMKSSL EEGISVLKSI KFSSSKWKKL IPQIPISINR SLPVSALDVL KYEEVDMESL VGVLPEPLEK YTACRELARR LKIEASYESV LSYQLQEIKE VQQDEALQLP HELDYLTIRD VSLSQEVREK LHLSRPQTIG AASRIPGVTP AAIINLLRFV RSTRQSRQQ
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.
基因功能參考文獻(xiàn)：
1. MTO1 mediates tRNA modification and controls mitochondrial translation rate in a highly tissue-specific manner associated with tissue-specific oxidative phosphorylation defects. PMID: 25552653
2. here described is an MTO1-deficient mouse model generated by gene trap mutagenesis that mirrors the human phenotype showing complex I defect and cardiomyopathy. PMID: 25506927
3. These observations suggest that the mouse MTO1 is a structural and functional homolog of yeast MTO1, thereby playing a role in the mitochondrial tRNA modification and protein synthesis. PMID: 14522080
亞細(xì)胞定位：

Mitochondrion.
蛋白家族：

MnmG family
組織特異性：

Ubiquitously expressed in various tissues, but with markedly elevated expression in tissues of high metabolic rates.
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:68291

STRING: 10090.ENSMUSP00000034896

UniGene: Mm.291779