Recombinant Mouse Protein FAM161A (Fam161a)

中文名稱：

小鼠Fam161a重組蛋白
貨號：

CSB-YP848082MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Fam161a重組蛋白
貨號：

CSB-EP848082MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Fam161a重組蛋白
貨號：

CSB-EP848082MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Fam161a重組蛋白
貨號：

CSB-BP848082MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Fam161a重組蛋白
貨號：

CSB-MP848082MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Fam161a
Uniprot No.：

Q8QZV6
別名：

Fam161aProtein FAM161A
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-448
氨基酸序列

MSKLEKMYQD KLNIKDIQAG FIRDGISDSS SSSASEKSCS HPALSVTSLS EPDLDGSSSL STTTDEGLPD LEEKTPGESS AMVHAQELIN NMWNDFSVED YIQYDSDSRT AKKKRKKAKS LTPKITVPVP FEMTVREQNR REKALSARSD LETKLLKRDE DDAECKKKFR ANPVPSCVLL PLYEDLVKQS EERRKKARER NRAALLASLK PFKFIAREEQ KQAVREKKLR DLFRAKRKTN QFKAKPVPRF IYRPAASDKP KEEELYGDSR MLPKVRDLLQ NSPWPSRSAC RRFRDPRSPA KPRGKHRRRC LRRDGDLEKW KEPFSEYSFL KCPMLCEECC LHESPCDSDK RQKLLADIRA DEEILRETRR PGRSPRRKSP GRSSNPKPRP HECSPPMPTA SSRGREQAIR RSEKARMREY WQELEEQEEK LQKRPMLFER VTQVVFIG
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Involved in ciliogenesis.
基因功能參考文獻(xiàn)：
1. Fam161a is required for the molecular delivery into the outer segment cilium, a function which is essential for outer segment disk formation and ultimately visual function. PMID: 24833722
2. FAM161A-associated RP can be considered as a novel retinal ciliopathy and that its molecular pathogenesis may be related to other ciliopathies. PMID: 22940612
3. Null mutations in FAM161A are responsible for the RP28-associated autosomal-recessive retinitis pigmentosa. PMID: 20705278
4. These data suggest a pivotal role for FAM161A in photoreceptors and reveal that FAM161A loss-of-function mutations are a major cause of autosomal-recessive Retinitis pigmentosa. PMID: 20705279
亞細(xì)胞定位：

Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Note=Localized in the region between the outer and inner photoreceptor segments, corresponding to the photoreceptor connecting cilium.
蛋白家族：

FAM161 family
組織特異性：

Expressed in the retina.
數(shù)據(jù)庫鏈接：

KEGG: mmu:73873

UniGene: Mm.252406