Recombinant Mouse Proprotein convertase subtilisin/kexin type 7 (Pcsk7), partial

中文名稱：

小鼠Pcsk7重組蛋白
貨號：

CSB-YP017646MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Pcsk7重組蛋白
貨號：

CSB-EP017646MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Pcsk7重組蛋白
貨號：

CSB-EP017646MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Pcsk7重組蛋白
貨號：

CSB-BP017646MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Pcsk7重組蛋白
貨號：

CSB-MP017646MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Pcsk7
Uniprot No.：

Q61139
別名：

Pcsk7; Pc7; Proprotein convertase subtilisin/kexin type 7; EC 3.4.21.-; Prohormone convertase 7; Proprotein convertase 7; PC7; Subtilisin-like proprotein convertase 7; SPC7; Subtilisin/kexin-like protease PC7
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive secretory pathway.
基因功能參考文獻：
1. PC7 has a critical role in normal processing of cholecystokinin in mouse brain PMID: 27923657
2. Data show that BDNF and PC7 mRNAs are colocalized in hippocampus and amygdala and that mature BDNF protein levels are reduced in these brain areas in proprotein convertase PC7 knockout mice. PMID: 24101515
3. Proprotein convertase PC7 enhances the activation of the EGF receptor pathway through processing of the EGF precursor. PMID: 21209099
亞細胞定位：

Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
蛋白家族：

Peptidase S8 family
組織特異性：

Widely expressed. Expressed in brain, lung, muscle, heart, liver, kidney, spleen and thymus.
數(shù)據(jù)庫鏈接：

KEGG: mmu:18554

STRING: 10090.ENSMUSP00000047508

UniGene: Mm.283283