Recombinant Mouse Prickle-like protein 2 (Prickle2), partial

中文名稱：

小鼠Prickle2重組蛋白
貨號：

CSB-YP800362MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Prickle2重組蛋白
貨號：

CSB-EP800362MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Prickle2重組蛋白
貨號：

CSB-EP800362MO-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Prickle2重組蛋白
貨號：

CSB-BP800362MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Prickle2重組蛋白
貨號：

CSB-MP800362MO
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Prickle2
Uniprot No.：

Q80Y24
別名：

Prickle2; Prickle-like protein 2
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

基因功能參考文獻(xiàn)：
1. The results of this study demonstrated that Prickle2 is required for normal ependymal motile cilia development and function. PMID: 24708399
2. Prickle2 disruption causes behavioral abnormalities like altered social interaction, learning abnormalities and behavioral inflexibility. In mouse hippocampal neurons, it reduced dendrite branching, synapse number and postsynaptic density size. PMID: 23711981
3. The cell polarity phenotype was efficiently rescued by nuclear but not cytoplasmic Prickle2, demonstrating the nuclear localization of Prickle2 is critical for its function. PMID: 22333836
4. The prickle2 protein is a novel PSD protein that interacts with PSD-95 and NMDA receptors through complex formations in the brain. PMID: 21324980
5. Putative planar cell polarity protein prickle-like 2 is distributed in crescents on the medial sides of vestibular epithelial cells before the morphological polarization of hair cells. PMID: 17376975
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亞細(xì)胞定位：

Nucleus membrane.
蛋白家族：

Prickle / espinas / testin family
組織特異性：

Expressed in the hippocampus and cerebral cortex.
數(shù)據(jù)庫鏈接：

KEGG: mmu:243548

STRING: 10090.ENSMUSP00000032093

UniGene: Mm.248820