Recombinant Mouse Plexin-B3 (Plxnb3), partial

中文名稱：

小鼠Plxnb3重組蛋白
貨號：

CSB-YP886176MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Plxnb3重組蛋白
貨號：

CSB-EP886176MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Plxnb3重組蛋白
貨號：

CSB-EP886176MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Plxnb3重組蛋白
貨號：

CSB-BP886176MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Plxnb3重組蛋白
貨號：

CSB-MP886176MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Plxnb3
Uniprot No.：

Q9QY40
別名：

Plxnb3; Kiaa1206; Plxn6; Plexin-B3; Plexin-6
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. Seem to be non-essential for normal development and function of the central nervous system.
基因功能參考文獻：
1. Data suggest that under physiological conditions Plexin-B3 is not essential for the development and function of the central nervous system. PMID: 19699796
2. Plexin-B3 is a functional receptor for semaphorin 5A PMID: 15218527
3. Plexin B3 strongly stimulates neurite outgrowth of primary murine cerebellar neurons. PMID: 16122393
4. These results help to better comprehend mechanisms used for plexin B3 transcriptional regulation. PMID: 18680721
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
蛋白家族：

Plexin family
組織特異性：

Expressed in brain (at protein level). In cerebellum, strongest expression detected in Purkinje and granular cells. Detected at very low levels in several fetal tissues, including dorsal root ganglia (DRG), heart, lung, optic bulb, brain and liver.
數據庫鏈接：

KEGG: mmu:140571

STRING: 10090.ENSMUSP00000002079

UniGene: Mm.275600