Recombinant Mouse Phosphomannomutase 2 (Pmm2)

中文名稱：

小鼠Pmm2重組蛋白
貨號：

CSB-YP018238MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Pmm2重組蛋白
貨號：

CSB-EP018238MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Pmm2重組蛋白
貨號：

CSB-EP018238MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Pmm2重組蛋白
貨號：

CSB-BP018238MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Pmm2重組蛋白
貨號：

CSB-MP018238MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Pmm2
Uniprot No.：

Q9Z2M7
別名：

Pmm2; Phosphomannomutase 2; PMM 2; EC 5.4.2.8
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-242
氨基酸序列

MATLCLFDMD GTLTAPRQKI TEEMDGFLQK LRQKTKIGVV GGSDFEKLQE QLGNDVVEKY DYVFPENGLV AYKDGKLLCK QNIQGHLGED VIQDLINYCL SYIANIKLPK KRGTFIEFRN GMLNVSPIGR SCSQEERIEF YELDKKEHIR QKFVADLRKE FAGKGLTFSI GGQISIDVFP EGWDKRYCLR HLEHAGYKTI YFFGDKTMPG GNDHEIFTDP RTVGYTVTAP EDTRRICEGL FP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
基因功能參考文獻：
1. This functional mouse model of PMM2-CDG, in vitro assays and identification of the novel gp130 biomarker all shed light on the human disease, and moreover, provide the essential tools to test potential therapeutics for this untreatable disease. PMID: 27053713
2. Pmm2 activity in jejunum increased during the early stages of life, and it decreased at 1 month old, as does the amount of mannose incorporated into glycoproteins, whereas in the ileum, they were not affected by age. PMID: 20523973
3. Pmm2 immunoreactivity seen in prenatal brain until postnatal and adult stage and restricted in neuronal cell bodies. PMID: 16115222
4. These results indicate that Pmm2 is essential for early development of mice. PMID: 16847317
亞細胞定位：

Cytoplasm.
蛋白家族：

Eukaryotic PMM family
數據庫鏈接：

KEGG: mmu:54128

STRING: 10090.ENSMUSP00000023396

UniGene: Mm.9699