Recombinant Mouse Otolin-1 (Otol1)

中文名稱：

小鼠Otol1重組蛋白
貨號：

CSB-YP681285MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Otol1重組蛋白
貨號：

CSB-EP681285MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Otol1重組蛋白
貨號：

CSB-EP681285MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Otol1重組蛋白
貨號：

CSB-BP681285MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Otol1重組蛋白
貨號：

CSB-MP681285MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Otol1
Uniprot No.：

Q4ZJM7
別名：

Otol1; Gm414; Otolin-1
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

24-482
氨基酸序列

KTTPYTK FTKKSEGKEM LKGLKPSSGF FLDGEETVHT ETAAMAEPTT GSPALAMAES TAGPSASATT RLLPFESFSL DTTGFVLNCC HCCSFVTGQK GEPGKMGKQG PKGETGDTGS PGHPGTTGPQ GPKGQKGEKG LKGDRGDQGA GGIPGYPGKP GEQGALGPKG DKGTIGPAGT KGQKGSKGEL CGNGTKGEKG DPGASGAHGF IGEPGAKGEK GGVGEKGYRG DLGERGEKGQ KGEKGMEGEK GSRGDVGSEG KRGSDGLPGL RGDSGPKGEK GEIGSPGFTG PAGPKGELGS KGVRGPTGKK GSRGVKGSKG EATQVPQSAF SALLSKPFPP PNVPIKFDKI LSNDQGDYSP VTGKFNCSVP GTYIFSYHVT VRGRPARISL VARNRKQFKS RETLYGQQVD QASLLLILKL SAGDQVWLEV SKDWNGLYVG PEDDSIFSGF LLYPEETFSK SP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Collagen-like protein specifically expressed in the inner ear, which provides an organic scaffold for otoconia, a calcium carbonate structure in the saccule and utricle of the ear. Acts as a scaffold for biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure. Together with OC90, modulates calcite crystal morphology and growth kinetics.
基因功能參考文獻：
1. Report otoconin 90 is attached to a scaffold consisting of the hexagonal fibrillar meshwork, characteristic of otolin, in the otoconia. PMID: 22841569
2. Otolin 1 interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1 in the inner ear. PMID: 20856818
3. Identification and functional characterization of a similar protein in zebrafish. PMID: 15905077
亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

OTOL1 family
組織特異性：

Expressed in the organic matrix of otoconia (at protein level). Expressed in neonatal sensory epithelium of vestibular utricle and saccule and also in otoconia.
數據庫鏈接：

KEGG: mmu:229389

STRING: 10090.ENSMUSP00000057607

UniGene: Mm.331071