Recombinant Mouse Nicotinate phosphoribosyltransferase (Naprt1)

中文名稱：

小鼠Naprt重組蛋白
貨號：

CSB-YP807484MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Naprt重組蛋白
貨號：

CSB-EP807484MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Naprt重組蛋白
貨號：

CSB-EP807484MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Naprt重組蛋白
貨號：

CSB-BP807484MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Naprt重組蛋白
貨號：

CSB-MP807484MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Naprt
Uniprot No.：

Q8CC86
別名：

Naprt; Naprt1; Nicotinate phosphoribosyltransferase; NAPRTase; EC 6.3.4.21; Nicotinate phosphoribosyltransferase domain-containing protein 1
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-538
氨基酸序列

MEMELDSEGR MVVRPLLTDL YQATMALGYW RAGRACEAAE FELFFRHCPF GGSFALSAGL QDCMRFLRAF RLRDADVQFL ASVLPPDTDP AFFEHLRALD CSGVTVRALP EGSLAFPGVP LLQVSGPLLL VQLLETPLLC LVSYASLVAT NAARLRLIAG PDKKLLEMGL RRAQGPDGGF TASIYSYLGG FDSSSNTLAG QLRGVPVAGT LAHSFVTSFS GSEVPPDPML APASSEGPTV DLPARVNLWL KRVCLYLGLE EQEPHPGERA AFVAYALAFP RAFQGLLDSY SVRRSGLPNF LAVALALGEL GYRAVGVRLD SGDLLQQAKE IRGIFRTAGA QFQMPWLESV PIAVSNNIDE SELMRLAQKG SEVNVIGIGT SVVTCPKQPS MGCVYKLVSV GGQPRIKLTE DPEKQTLPGS KAAFRFLGPD GSLLLDLLQL AEEPPPKAGQ ELRVWPRGTQ EPCTVKPAQV EPLLRLYLQQ GQLCEPLPSL DESRRFAQQS LSLLRPAHKQ LQSPAVYPVA LSEKLRALVD SLSARGPL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis.
基因功能參考文獻：
1. Synthesis and Degradation of Adenosine 5'-Tetraphosphate by Nicotinamide and Nicotinate Phosphoribosyltransferases PMID: 28416276
2. NA elevates cellular NAD levels through NAPRT function and, thus, protects the cells against stress, partly due to lack of feedback inhibition of NAPRT but not NamPRT by NAD PMID: 17604275
亞細胞定位：

Cytoplasm, cytosol.
蛋白家族：

NAPRTase family
組織特異性：

Abundantly expressed in the small intestine, liver and kidney.
數據庫鏈接：

KEGG: mmu:223646

STRING: 10090.ENSMUSP00000023237

UniGene: Mm.288368